Gadd45 Stress Sensor Genes
- Indbinding:
- Paperback
- Sideantal:
- 164
- Udgivet:
- 5. Maj 2023
- Udgave:
- 23002
- Størrelse:
- 178x10x254 mm.
- Vægt:
- 322 g.
- 2-3 uger.
- 9. Oktober 2024
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Beskrivelse af Gadd45 Stress Sensor Genes
This second edition is fully updated throughout and covers the emerging evidence that indicates that the Gadd45 family of proteins plays a unique and critical role as sensors of stress, including genotoxic, physiological, and oncogenic stress. It sheds light on the complex cellular stress response, encompassing myriad molecular pathways with a plethora of regulators and effectors.
The GADD45 stress response genes encode small (18 kd) nuclear/cytoplasmic proteins. These genes are rapidly induced by a wide variety of endogenous and exogenous stress stimuli. Despite marked similarities, Gadd45 genes are regulated differentially and exhibit functional diversity. Gadd45 proteins respond to physiological and oncogenic stress, and are implicated in cell cycle arrest, DNA demethylation and repair, apoptosis, cell survival, genomic stability, and inflammation.
The purpose of this book is to provide a comprehensive overview of the unique global role that Gadd45proteins play as stress sensors and the molecular pathways involved.
The GADD45 stress response genes encode small (18 kd) nuclear/cytoplasmic proteins. These genes are rapidly induced by a wide variety of endogenous and exogenous stress stimuli. Despite marked similarities, Gadd45 genes are regulated differentially and exhibit functional diversity. Gadd45 proteins respond to physiological and oncogenic stress, and are implicated in cell cycle arrest, DNA demethylation and repair, apoptosis, cell survival, genomic stability, and inflammation.
The purpose of this book is to provide a comprehensive overview of the unique global role that Gadd45proteins play as stress sensors and the molecular pathways involved.
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Bogen Gadd45 Stress Sensor Genes findes i følgende kategorier:
- Business og læring > Videnskab
- Lægevidenskab og sygepleje > Præklinisk medicin: basale fag > Medicinsk genetik
- Matematik og naturvidenskab > Biologi og biovidenskab > Biovidenskab: generelle emner > Genetik (ikke-medicinsk)
- Matematik og naturvidenskab > Biologi og biovidenskab > Mikrobiologi (ikke-medicinsk)
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