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  5. Total Synthesis of Bioactive Natural Products by Palladium-Catalyzed Domino Cyclization of Allenes and Related Compounds

Total Synthesis of Bioactive Natural Products by Palladium-Catalyzed Domino Cyclization of Allenes and Related Compounds

af Shinsuke Inuki

indgår i Springer Theses serien

Total Synthesis of Bioactive Natural Products by Palladium-Catalyzed Domino Cyclization of Allenes and Related Compounds af Shinsuke Inuki
Bag om Total Synthesis of Bioactive Natural Products by Palladium-Catalyzed Domino Cyclization of Allenes and Related Compounds

Based on these methodologies, enantioselective total syntheses of bioactive natural products, pachastrissamine (26% overall yield in seven steps), lysergic acid (4.0% overall yield in fifteen steps), lysergol (3.6% overall yield in fifteen steps) and isolysergol (8.2% overall yield in eleven steps) have been achieved.

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  • Sprog:
  • Engelsk
  • ISBN:
  • 9784431540427
  • Indbinding:
  • Hardback
  • Sideantal:
  • 106
  • Udgivet:
  • 22. november 2011
  • Udgave:
  • 2012
  • Størrelse:
  • 234x156x7 mm.
  • Vægt:
  • 360 g.
  • 8-11 hverdage.
  • 11. februar 2025

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Beskrivelse af Total Synthesis of Bioactive Natural Products by Palladium-Catalyzed Domino Cyclization of Allenes and Related Compounds

Based on these methodologies, enantioselective total syntheses of bioactive natural products, pachastrissamine (26% overall yield in seven steps), lysergic acid (4.0% overall yield in fifteen steps), lysergol (3.6% overall yield in fifteen steps) and isolysergol (8.2% overall yield in eleven steps) have been achieved.

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