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Single-particle Cryo-EM of Biological Macromolecules

Bag om Single-particle Cryo-EM of Biological Macromolecules

This edited book is written for students, postdocs and established investigators who want to enter the field of single-particle cryo-EM. This is a recently developed method to determine high-resolution structures of biological macromolecules. A major strength is the fact that cryo-EM does not require prior crystallization of protein complexes. It is especially well suited for larger complexes and molecular machines. This book, provides a comprehensive, accessible and authoritative introduction to the field. It covers all necessary background, ranging from the underlying concepts to practical aspects such as specimen preparation, data-collection, data analysis, and the final validation of results. Key features Written for students, postdocs and established investigators who want to enter the field of single-particle cryo-EMProvides a comprehensive, accessible and authoritative introduction to the field of high-resolution structure analysis by single-article cryo-EMCovers all necessary background, ranging from the underlying concepts to practical aspects such as specimen preparation, data-collection, data analysis, and the final validation of resultsAuthors of individual sections of this book have been recruited from among the most authoritative leaders in each topic

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  • Sprog:
  • Engelsk
  • ISBN:
  • 9780750330374
  • Indbinding:
  • Hardback
  • Sideantal:
  • 318
  • Udgivet:
  • 19. maj 2021
  • Størrelse:
  • 264x185x27 mm.
  • Vægt:
  • 782 g.
  • 2-3 uger.
  • 14. december 2024

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Beskrivelse af Single-particle Cryo-EM of Biological Macromolecules

This edited book is written for students, postdocs and established investigators who want to enter the field of single-particle cryo-EM. This is a recently developed method to determine high-resolution structures of biological macromolecules. A major strength is the fact that cryo-EM does not require prior crystallization of protein complexes. It is especially well suited for larger complexes and molecular machines. This book, provides a comprehensive, accessible and authoritative introduction to the field. It covers all necessary background, ranging from the underlying concepts to practical aspects such as specimen preparation, data-collection, data analysis, and the final validation of results.

Key features

Written for students, postdocs and established investigators who want to enter the field of single-particle cryo-EMProvides a comprehensive, accessible and authoritative introduction to the field of high-resolution structure analysis by single-article cryo-EMCovers all necessary background, ranging from the underlying concepts to practical aspects such as specimen preparation, data-collection, data analysis, and the final validation of resultsAuthors of individual sections of this book have been recruited from among the most authoritative leaders in each topic

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