Semantic Breakthrough in Drug Discovery
- Indbinding:
- Paperback
- Sideantal:
- 144
- Udgivet:
- 31. oktober 2014
- Størrelse:
- 191x9x235 mm.
- Vægt:
- 284 g.
- 2-3 uger.
- 30. november 2024
På lager
Normalpris
Abonnementspris
- Rabat på køb af fysiske bøger
- 1 valgfrit digitalt ugeblad
- 20 timers lytning og læsning
- Adgang til 70.000+ titler
- Ingen binding
Abonnementet koster 75 kr./md.
Ingen binding og kan opsiges når som helst.
- 1 valgfrit digitalt ugeblad
- 20 timers lytning og læsning
- Adgang til 70.000+ titler
- Ingen binding
Abonnementet koster 75 kr./md.
Ingen binding og kan opsiges når som helst.
Beskrivelse af Semantic Breakthrough in Drug Discovery
The current drug development paradigm---sometimes expressed as, ``One disease, one target, one drug''---is under question, as relatively few drugs have reached the market in the last two decades. Meanwhile, the research focus of drug discovery is being placed on the study of drug action on biological systems as a whole, rather than on individual components of such systems. The vast amount of biological information about genes and proteins and their modulation by small molecules is pushing drug discovery to its next critical steps, involving the integration of chemical knowledge with these biological databases. Systematic integration of these heterogeneous datasets and the provision of algorithms to mine the integrated datasets would enable investigation of the complex mechanisms of drug action; however, traditional approaches face challenges in the representation and integration of multi-scale datasets, and in the discovery of underlying knowledge in the integrated datasets. The Semantic Web, envisioned to enable machines to understand and respond to complex human requests and to retrieve relevant, yet distributed, data, has the potential to trigger system-level chemical-biological innovations. Chem2Bio2RDF is presented as an example of utilizing Semantic Web technologies to enable intelligent analyses for drug discovery.Table of Contents: Introduction / Data Representation and Integration Using RDF / Data Representation and Integration Using OWL / Finding Complex Biological Relationships in PubMed Articles using Bio-LDA / Integrated Semantic Approach for Systems Chemical Biology Knowledge Discovery / Semantic Link Association Prediction / Conclusions / References / Authors' Biographies
Brugerbedømmelser af Semantic Breakthrough in Drug Discovery
Giv din bedømmelse
For at bedømme denne bog, skal du være logget ind.Andre købte også..
Find lignende bøger
Bogen Semantic Breakthrough in Drug Discovery findes i følgende kategorier:
- Business og læring > Computer og IT
- Krop og sind
- Matematik og naturvidenskab > Matematik
- Filosofi og religion > Filosofi > Emner i filosofi > Filosofi: metafysik og ontologi
- Databehandling og informationsteknologi > Computere og hardware > Netværkskomponenter
- Databehandling og informationsteknologi > Programmering / softwareudvikling > Webprogrammering
- Databehandling og informationsteknologi > Anvendt databehandling
© 2024 Pling BØGER Registered company number: DK43351621