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Noninferiority Testing in Clinical Trials

- Issues and Challenges

Bag om Noninferiority Testing in Clinical Trials

Requiring no prior knowledge of NI testing, this book explains how to choose the NI margin as a small fraction of the therapeutic effect of the active control in a clinical trial. It discusses issues with estimating the effect size based on historical placebo control trials of the active control. The author covers basic concepts related to NI tr

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  • Sprog:
  • Engelsk
  • ISBN:
  • 9780367576028
  • Indbinding:
  • Paperback
  • Sideantal:
  • 208
  • Udgivet:
  • 30. juni 2020
  • Størrelse:
  • 156x234x0 mm.
  • Vægt:
  • 453 g.
  • 2-4 uger.
  • 18. december 2024
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Requiring no prior knowledge of NI testing, this book explains how to choose the NI margin as a small fraction of the therapeutic effect of the active control in a clinical trial. It discusses issues with estimating the effect size based on historical placebo control trials of the active control. The author covers basic concepts related to NI tr

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