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NMR-Bioassay Guided Isolation of the Natural 20S Proteasome Inhibitors from Photorhabdus Luminescens

- A Novel NMR-Tool for Natural Product Detection

Bag om NMR-Bioassay Guided Isolation of the Natural 20S Proteasome Inhibitors from Photorhabdus Luminescens

Martin Stein's thesis describes a novel methodology for natural product discovery. The author demonstrates the extraordinary value of this approach by the successful isolation of two potent inhibitors of the pharmaceutically relevant proteasome core particle from the insect pathogen photorhabdus luminescens.

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  • Sprog:
  • Engelsk
  • ISBN:
  • 9783319383996
  • Indbinding:
  • Paperback
  • Sideantal:
  • 71
  • Udgivet:
  • 1. oktober 2016
  • Udgave:
  • 12014
  • Størrelse:
  • 235x155x5 mm.
  • Vægt:
  • 1474 g.
  • 8-11 hverdage.
  • 5. december 2024
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Martin Stein's thesis describes a novel methodology for natural product discovery. The author demonstrates the extraordinary value of this approach by the successful isolation of two potent inhibitors of the pharmaceutically relevant proteasome core particle from the insect pathogen photorhabdus luminescens.

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