Nightwalker

Stormwalker Janet Begay, proprietor of the Crossroads Hotel, a place where the paranormal stop for a safe night's rest, is awakened in the night when a slayer comes to kill Ansel, a Nightwalker who's become a more-or-less permanent resident and Janet's friend.
When Janet and dragon-shifter Mick intervene to save Ansel's un-life, they find that the attack is the beginning of an oncoming storm. Janet already has her hands full with her crazy half-sister, the upcoming marriage of her father, the return of a woman who claims to be Coyote's wife, a couple of dragons on her back, and her worry about Mick, who's behaving strangely again.
But it seems that everyone is after Ansel, who fears he killed the woman he loves in a Nightwalker frenzy. Janet must choose between protecting Ansel or facing the most powerful magical beings in the world, who are willing to destroy Janet, Mick, her hotel, and everyone she cares about to get to Ansel and his secrets.
Book 4 of the Stormwalker series.