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Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials

af Meinhard Kieser

indgår i Springer Series in Pharmaceutical Statistics serien

Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials af Meinhard Kieser
Bag om Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials

This book provides an extensive overview of the principles and methods of sample size calculation and recalculation in clinical trials. Blinded sample size recalculation procedures for internal pilot study designs are considered, as well as methods for sample size reassessment in adaptive designs that use unblinded data from interim analyses.

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  • Sprog:
  • Engelsk
  • ISBN:
  • 9783030495275
  • Indbinding:
  • Hardback
  • Sideantal:
  • 396
  • Udgivet:
  • 20. november 2020
  • Udgave:
  • 12020
  • Størrelse:
  • 241x162x32 mm.
  • Vægt:
  • 756 g.
  • 8-11 hverdage.
  • 6. december 2024
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This book provides an extensive overview of the principles and methods of sample size calculation and recalculation in clinical trials. Blinded sample size recalculation procedures for internal pilot study designs are considered, as well as methods for sample size reassessment in adaptive designs that use unblinded data from interim analyses.

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