Bøger i Interdisciplinary Biotechnolog serien

Biotechnology involves an interdisciplinary science that provides an interface between biological, molecular and cellular aspects of living organisms with broad technologies applicable in the fields of health, environment and materials. This book ¿Biotechnology applied to inflammatory diseases: Cellular mechanisms and nanomedicine¿ is focused on elaborating especially on two trendy areas from Biotechnology. In this volume, different inflammatory pathologies in terms of cellular and molecular mechanisms are characterized to better understand the science behind current precision medicine. The second part of the book focuses on the main biotechnological advancements for the understanding of the molecular mechanisms involved in the progression of various types of inflammatory diseases, highlighting up-to-date contributions of nanomedicine. The reader will be able to explore the utilization of technologies for various inflammatory diseases and will be able to enable an engaging and valuableknowledge for further research and clinically applied scenarios.

This book updates knowledge on recent advances in computational, biophysical and bioinformatics tools/techniques and their practical applications in modern drug design and discovery paradigm. It also encompasses fundamental principles, advanced methodologies and applications of various CADD approaches including several cutting-edge areas; presenting recent developments covering ongoing trends in the field of computer-aided drug discovery. Having contributions by a global team of experts, the book is expected to be an ideal resource for drug discovery scientists, medicinal chemists, pharmacologists, toxicologists, phytochemists, biochemists, biologists, R&D personnel, researchers, students, teachers and those working in the field of drug discovery. It will fill the knowledge gaps that exist in the current CADD approaches and methodologies/ protocols being widely used in both academic and research practices. Further, a special focus on current status of various computational drug design approaches (SBDD, LBDD, de novo drug design, pharmacophore-based search), bioinformatics tools and databases, computational screening and modeling of phytochemicals/natural products, artificial intelligence and machine learning, and network pharmacology and systems biology would certainly guide researchers, students or readers to conduct their research in the emerging area(s) of interest. It is also expected to be highly beneficial to various stakeholders working in the pharmaceutical and biotechnology industries (R&D), the academic as well as research sectors.

This book ¿Microbial Products for Future Industrialization¿ focuses on the exploitation of various advanced microbial and molecular biology technologies and their associated processes, especially the microbial-molecular-chemical nexus, for the future industrialization of emerging new microbial products. The descriptions given in its chapters take the reader through an entire journey of new emerging microbial products from lab to industry and provide new information that has not yet been fully exploited for future industrialization steps. This volume is a great resource for readers seeking a more comprehensive material covering the technical, economic, and societal aspects that impact bioprocessing of microbial products at the industrial level along with biotechnological intervention for better production of microbial products in near future. This book also encompasses advanced and updated information as well as future directions for young researchers and scientists, and academics who are working in the field of microbial product production related to sustainability.

This is the first book to explore the science underlying the Jerusalem artichoke, which is also known as Helianthus tuberosus L. and it is attracting increasing interest among food scientists and professionals worldwide. Due to a wide perspective for the production of inulin due to its high economic and ecological importance, the development of technologies for isolating and processing tuberous sunflower raw materials using environmentally friendly technologies (green chemistry and white biotechnology) and the global production of inulin shows an increasing tendency. Here we focus on the latest technological achievements related to the use of inulin in the food processing. In this book, readers will find full explanation of the conceptual aspects and the latest research results on a wide range of topics, including the relevant characteristics and applications from various fields. Written by leading scientists in the field, the book will be a valuable resource for students and researchers in the fields of food chemistry, nutritional science, physiology, and bioengineers, as well as for professionals in the food industry.

This book provides a comprehensive introduction and review of state-of-the-art biotechnological tools in enhancement of bioactive compounds in medicinal and aromatic plants. Plant bioactive compounds are plant-based natural products that display a variety of pharmacological applications. These bioactive compounds are important as medicines, pigments, flavorings and drugs because most of the pharmaceutical industries are highly dependent on medicinal plants and their extraction. The book introduces a systematic overview of state-of-the-art biotechnological techniques such as Omics, Crisper /Cas9 and RNAi to enhance the plant bioactive contents as well as enlists various in vitro techniques, hairy root culture and transgenic technology to enhance plant bioactive contents using plant tissue culture approaches. The book also provides an overview of the role of induced mutation, biotic and abiotic stress to increase the bioactive contents in plants and discusses the significant role of endophytes to enhance the contents of plant bioactive compound. The book also opens discussions related to standard operating procedures using hydroponics system of cultivation for significant enhancement of bioactive compound(s) and much more. This book serves as an excellent reference book for the researchers working in the field of plant secondary metabolites and pharmaceutical industries at global level.