Bøger udgivet af Springer Science+Business Media

The recent intro duction of PTH as a major therapeutic agent in osteoporosis has directed renewed interest in this important hormone and in the physiology of the parathyroid gland.

Once techniques to probe the methylation profile of whole genomes as well as specific genes became available, it became clear that DNA methylation patterns are gene and tissue specific and that patterns of gene expression correlate with patterns of methylation.

New experimental observations often require fresh concepts for their interpretation, and at times even changes of paradigms. For the above reasons, the idea to organize a symposium addressing the new developments in angiogenesis research was received with enthusiasm by all those involved in its preparation.

Cell adhesion is one of the most important properties controlling embryonic development. The identifica tion of several families of adhesion molecules, well conserved throughout evolu tion, has been the basis of a considerable amount of work over the past 20 years that contributed to establish functions of cell adhesion in almost all organs.

Focuses on the status of Ca2+ ions in regulation of phototransduction, light adaptation and the recovery phase in vertebrate photoreceptors. This book emphasises on Ca2+-binding proteins and their targets, among them particulate guanylate cyclases, GPCR-coupled kinases and cyclic nucleotide-gated cation channels.

The discovery of biological activity associated with flavonoid contaminants in vitamin C preparations from bell peppers and lemons by Szent-Gyorgyi and his associates opened a floodgate of research into the biological functions of this ubiquitous and diverse group of compounds.

Further, developmental cell remodeling during tissue maturation involves programmed cell death as the major mechanism for functional and structural safe transition of undifferentiated cells to more specialized counterparts.

This series of books, which is published at the rate of about one per year, addresses fundamental problems in materials science.

Presents a discussion of the biological effects produced following the metabolism of xenobiotic chemicals to chemically reactive metabolites. This volume covers structure-activity relationships, advances in the chemistry of reactive metabolites, and the generation and activity of reactive oxygen species with special emphasis on nitric oxide.

The major emphasis in this book is a compilation and definition of what is known about components of human milk, including glycoconjugates, that inhibit common pathogens of the infant. Also discussed are other bioactive constituents whose relevant biological roles are also beginning to be defined.

This volume summarizes current research on the influence of plant polyphenols on human health, promoting collaboration between chemists and biologists to improve our understanding of their biological significance, and expanding the possibilities for their use.

This volume is designed to motivate and engage scientists, policymakers, and practitioners to greater scientific discourse, reduce the stigma on and validate the importance of women's sexual and reproductive health.

It contains scientific discussions of dynamic brain changes (genetics, structure, physiology and hormones) plasticity of the central nervous system, functional reorganization and brain repair in response to treatment in all stages, and emphasizes acute care of early and precise diagnostics.

Despite the sense of uniqueness implicit in phrases like "the biodiversity crisis," meant to convey the notion that the present bout of extinctions is by far the worst endured in recent times, substantial losses have occurred throughout near time.

Proceedings of a NATO ASI held in Antalya, Turkey, August 31 - September 11, 1997

This book employs computer-assisted Associative Group Analysis technology of comparative imaging and cognitive mapping to identify these factors and offers new perspectives for more comprehensive risk assessments and effective prevention.

Volume 16 marks the beginning of a special topic series devoted to modern techniques in protein NMR, under the Biological Magnetic Resonance series.

Proceedings of the VIIth International Symposium held in Segovia, Spain, May 10-15, 1997

In the late 1980s, it became painfully evident to the pharmaceutical industry that the old paradigm of drug discovery, which involved highly segmented drug - sign and development activities, would not produce an acceptable success rate in the future.

Proceedings of the Seventh International Conference held in Banff, Canada, October 22-27, 1996

This is the third volume of Advances in Microbial Ecology to be produced by the current editorial board. Volume 15 is no exception in that we have a balance between the prokaryo tic and eukaryotic organisms and a range of subject matter from applied ecology through process ecology to ecological theory.

Science teachers come in many varieties, but they share a common goal: to nurture learners. Scientists teamed with teachers and their students represent a very real and rich opportunity to involve students in real science as practiced.

Proceedings of a NATO ARW held in Miami, Florida, October 14-18, 1995.

Proceedings of a NATO ASI held in Les Houches, France, June 13-23, 1995

Proceedings of a workshop held in Santa Fe, New Mexico, October 24-28, 1994

The focus of Volume I of the Handbook of Human Brain Function was on basic scientific principles of brain imaging as it relates to the study of human brain function. Such is the status of brain imaging in the study of clinical applications human brain function.

Until recent advents in neuroimaging, the brain had been inaccessible to in vivo visualization, short of neurosurgical procedures or some unfortunate traumatic exposure. Thus, one would take whatever information might be available and infer what regions of the brain were involved but could never actually visualize the brain.

Scientific advances over the past two decades have afforded unprecedented oppor tunities to understand the structure and function of receptors, receptor-ligand interactions, and receptor signaling.

Proceedings of a NATO ARW held in Erice, Italy, July 27-August 4, 1994

Proceedings of a NATO ARW held in New York City, June 2-5, 1993.