Bøger udgivet af IntechOpen

This book synthesizes the key concepts of immunosuppression and immunomodulation. A comprehensive understanding of these processes is necessary to develop vaccines and therapeutic interventions for diseases. This book examines the role of information molecules such as cytokines and chemokines and other proteins secreted by the host upon interacting with the pathogen(s) that modulate and suppress the immune system and assist the pathogen(s) in causing disease. Chapters discuss the modulation of inflammation, signaling pathways, the interaction of immune cells, and resulting immunity as well as its suppression.

Knowledge of retinal diseases has radically changed over the past 10 years with the development of both new techniques and instrumentation, with improvements in surgical machines and diagnostic tools. This book reports the latest developments in retinal diseases, from pathogenesis to diagnosis, and both medical and surgical approaches in the management of retinal diseases. The core of the book focuses on developments and new perspectives in the treatment of some retinal diseases. It also discusses the pathophysiology and treatment of retinal diseases, taking biological disease markers into consideration. The indications for surgery have expanded dramatically and inoperable conditions have become amenable to surgical treatment. As such, the book also provides a comprehensive overview of the current state of the art in the surgical approach to many vitreoretinal diseases with the latest developments in surgery of the retina that enable improved surgical outcomes.

Although the concept of using advanced therapy products such as stem cells seems to be a key strategy in the treatment of various diseases, much information in this area remains unknown. Stem cell products are highly complex, much more complex than chemical-based drugs. More and more often there are data indicating the risk of using stem cells. These risks are determined by various factors that are related to quality, biological activity, and the use itself, and thus administration. Therefore, it is very important to constantly systematize knowledge in this area. This book was created to present both the perspective of basic research, including the manipulation and changes in the properties of cells, and the changes and novelties in therapies themselves.

Skin wounds are common occurrences that result from the breakdown of anatomical continuity and integrity of the epidermis, with consequent functional changes. Wound healing is a complex phenomenon through which there is healing of the skin. The wound healing process begins immediately after the wound occurs and can be a lengthy and complex process depending on the severity of the wound and the normal or abnormal healing progress. Wound healing progress through three distinct phases of inflammation, proliferation, and remodeling in a methodical and complex sequence that involves cellular, molecular, and humoral mechanisms of action. Any change in this sequence of events can lead to abnormal wound healing. Due to the health and psychological consequences of wounds that are difficult to heal there has been a continuous effort to develop new therapies that promote wound healing more quickly and effectively and that restore the skin¿s barrier function. Nevertheless, this situation remains a medical challenge. This book presents some therapeutic advances based on new and innovative therapeutic options, medical devices, and biomaterials to promote wound healing. It is a theoretical and practical reference for future research on chronic wound healing.

Vegetation Dynamics, Changing Ecosystems and Human Responsibility provides an overview of vegetation dynamics, which is the science of natural, near-natural, and human-influenced changes in vegetation over time and space. We can find chapters about almost every viewpoint of this very diverse segment of our science and in connection with almost every main type of terrestrial ecosystem.

This book provides a comprehensive overview of cardiovascular diseases (CVDs) and associated conditions. It is organized into three sections on ¿Cardiovascular Pathophysiology¿, ¿Cardiovascular Diagnostics¿, and ¿Cardiovascular Treatments¿. Chapters address such topics as the role of obesity in CVD, cardiotoxicity, cardio-oncology, CVD in different disease states, modalities for detecting CVD, interventional strategies to prevent or treat CVD, and much more.

Unlock the transformative power of blockchain technology with Blockchain Applications - Transforming Industries, Enhancing Security, and Addressing Ethical Considerations. This edited volume brings together leading experts and their thought-provoking chapters on blockchain¿s diverse applications. From healthcare to finance and from energy to supply chain, delve into the latest advancements in cybersecurity, smart contracts, and audit digitalization. Discover how blockchain is revolutionizing the tourism industry and enabling decentralized autonomous organizations. Explore the potential of deep learning for disease detection and gain insights into the legal and market challenges of non-fungible tokens (NFTs). With real-world examples and case studies, this book showcases blockchain¿s tangible benefits, which include increased transparency, enhanced security, and improved efficiency. It also improves understanding of the ethical considerations and regulatory implications surrounding blockchain adoption for responsible implementation. This invaluable resource is for professionals, researchers, and technology enthusiasts alike, offering unique perspectives and cutting-edge research. Join us on a captivating journey through the world of blockchain applications. Experience its potential to reshape industries, enhance security, and pave the way for a transparent and decentralized future. Discover the keywords defining this volume: blockchain technology, transformative potential, cybersecurity, smart contracts, decentralized autonomous organizations, deep learning techniques, non-fungible tokens, transparency, security, efficiency, ethical considerations, regulatory implications, real-world examples, and cutting-edge research. Embrace the revolution and unlock the limitless possibilities of blockchain technology.

As a parent, guardian, or healthcare provider, ensuring the oral health of children is a vital aspect of overall health and well-being. Pediatric Dentistry - A Comprehensive Guide is an insightful book that covers critical concepts and clinical studies in pediatric dentistry to provide a comprehensive understanding of oral health in children. Chapters address such topics as the "dental home" concept, which involves early dental visits and establishing a dental home for children to prevent oral health issues, stomatognathic dysfunction, the role of the community in promoting good oral health in children, the effects of malnutrition on pediatric oral health, and the role of metals in pediatric oral health. The book is a valuable resource for pediatric dentists, dental hygienists, and other healthcare providers interested in promoting and maintaining oral health in children. It also serves as a guide for parents and guardians seeking to ensure optimal oral health for their children.

In a world shaped by the forces of nature, humankind has always sought to understand and mitigate the impacts of natural hazards. Natural Hazards - New Insights delves into the intricate realm of floods, earthquakes, tsunamis, meteoritical hazards, mining-related disasters, and other major catastrophes that afflict our planet. This book takes readers on a journey to gain a deeper understanding of these phenomena, unearthing fresh insights into their causes, impacts, and strategies to mitigate their effects. Organized into six comprehensive sections, this book begins with a global perspective on natural hazards, laying the foundation for understanding the diverse range of challenges they pose. It then explores seismic hazards, analyzing earthquake patterns, urban damage assessment, fault reactivation, and more. Shifting the focus to flooding as a natural hazard, the book examines hydrological extremes, flood mapping, and risk reduction strategies. It further explores climatological hazards, including the intricate relationship between climate change and natural disasters, remote sensing technologies, and the impacts of climate change on agriculture. Landslides are also scrutinized as significant natural hazards, with chapters on polarization analysis, landslide assessment, hazard zonation, and the impact of underground coal mining methods on slope stability. Lastly, the book addresses the social challenges that arise when disasters strike, examining psychological reactions, spontaneous volunteers, urban planning responses, and social vulnerability to earthquake hazards. Through peer-reviewed chapters, this book offers valuable insights and expertise from renowned authors in the field. Their contributions have shaped this comprehensive exploration, which aims to navigate the challenges, minimize risks, and build a safer and more sustainable environment for future generations.

Smart Mobility - Recent Advances, New Perspectives and Applications explores the rapidly evolving world of connected and autonomous vehicles, providing a comprehensive look at the latest advancements and cutting-edge technologies driving this exciting industry forward. This book covers the most pressing topics in smart mobility, including sizing, sensing, simulations, safety, and cybersecurity applications, giving readers a deep understanding of the challenges and opportunities facing this emerging field. With perspectives from leading experts, the book provides insights into the future of mobility and the role that technology will play in shaping our transportation systems. Whether you are a student, engineer, or industry professional, this book offers a unique and valuable resource for those looking to stay ahead of the curve in the ever-evolving world of smart mobility and its growing impact on our daily lives.

This edited volume is a collection of reviewed and relevant research chapters concerning developments within the field of phylogenetics. The book includes scholarly contributions by various authors, edited by experts pertinent to the field of phylogenetics. Each contribution comes as a separate chapter but is directly related to the book's topics and objectives. The target audience comprises scholars and specialists in the field.

Flame retardants reduce the risk of fire by decreasing the combustion rate and flame propagation in the presence of fire, leading to the prevention and control of fire. Flame Retardants is divided into four sections: section 1 consists of the introduction, section 2 discusses properties, Section 3 comprises nanocomposites, and section 4 includes computational analysis. The book will be useful for scientists and researchers interested in the field of fire control.