Bøger udgivet af Elsevier Science Publishing Co Inc

Genetic Disease Discovery and Therapeutics presents information on the methods used to determine how specific gene defects influence pathology and phenotype and to review novel therapeutic approaches designed for the treatment of specific genetic and genomic disorders.This book investigates methodologies applied to the characterization of downstream functional effects of specific gene mutations associated with altered phenotypes and clinical disease. It documents evidence of how specific mutations influence pathology and lead to disease manifestations. This book also reviews information on therapeutic approaches that could potentially be applied in diseases due to gene defects. Genetic Disease Discovery and Therapeutics is a valuable reference for scientists and graduate students involved in laboratory research related to genetics, physiology, pathology, and pharmacology as well as clinicians who encounter patients with genetic disorders.

A New Era in Alzheimer's Research: Pathogenesis, Prevention, and Treatment is focused on the research and perspectives in Alzheimer's disease (AD), offering an update on the challenging aspects of neurodegenerative disorders. Each chapter of this book contains unique and valuable scientific information on the latest progress of research in neurodevelopmental diseases. Even after years of research, Alzheimer's disease is still far from being cured; this book addresses the most current issues within the many dimensions relevant to the pathogenesis, diagnosis, and prevention under one cover, making it useful for researchers, students, and clinicians, as well as those in pharmaceuticals.

While there is a nearly universal agreement that drinking tea can benefit health, information on the benefits or adverse effects of drinking tea is scattered, leaving definitive answers difficult to ascertain. Tea in Health and Disease Prevention, Second Edition, once again addresses this problem, bringing together all the latest and most relevant information on tea and its health effects into one comprehensive resource. This book covers compounds in black, green, and white teas and explores their health implications, first more generally, then in terms of specific organ systems and diseases. With over 75% brand new content, this fully reorganized, updated edition covers a wider range of tea varieties and beneficial compounds found in tea, such as epigallocatechin gallate and antioxidants.Tea in Health and Disease Prevention, Second Edition, is an organized, efficient resource that will help readers find quick answers to questions and will help inspire further studies for those interested in tea research. This is a must-have reference for researchers in food science and nutrition, as well as nutritionists and dieticians.

For decades, Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics has served as the ultimate resource for clinicians integrating genetics and genomics into medical practice. With detailed coverage in contributions from more than 250 of the world’s most trusted authorities in medical genetics and a series of 11 volumes available for individual sale, the seventh edition of this classic reference includes the latest information on seminal topics such as prenatal diagnosis, genome sequencing, public health genetics, and genetic counseling. Volumes 3-11 cover diagnosis, management, and treatment of both rare and common disorders in all organ systems. Students, medical providers, and researchers all benefit from the latest information about the role of the genome in health and disease. This comprehensive yet practical resource emphasizes theory and research fundamentals across the full spectrum of applications to medicine. In this volume, leading physicians and researchers thoroughly examine medical genetics and genomics as applied to endocrine, skin, connective tissue and skeletal disorders, with emphasis on understanding the genetic mechanisms underlying these conditions, diagnostic approaches, and treatment methods that make use of current genomic technologies and translational studies. With regular advances in genomic technologies propelling precision medicine into the clinic, Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics, seventh edition, bridges the gap between high-level molecular genetics and genomics and practical application and serves as an invaluable clinical tool for the health professionals and researchers.

Coffee in Health and Disease Prevention, Second Edition, presents a comprehensive look at the compounds in coffee, their benefits (or adverse effects), and explores coffee as it relates to specific health conditions. Embracing a holistic approach, this book covers the coffee plant, coffee production and processing, the major varieties of coffee, and its nutritional and compositional properties. Coffee’s impact on human health, disease risk, and prevention comprises the majority of the text. Diseases covered including Alzheimer’s, anxiety and depression, asthma, diabetes, cancer, and more. This book also covers coffee’s impact on organs and organ systems, including the cardiovascular system, the nervous system, and the gut microbiome.Coffee in Health and Disease Prevention, Second Edition, is the only book on the market that covers all varieties of coffee in one volume and their potential benefits and risks to human health. This is an essential reference for researchers in nutrition, dietetics, food science, biochemistry, and public health.

The Whole Person explores the realms of theory and philosophy concerning minds and persons. This book presents models of the emergent realization of multiple mental processes, and of the constitution of social realities and social persons. Each chapter explores prevalent theoretical and philosophical assumptions that obstruct the acceptance of models depicting emergent realization, offering analyses of these barriers, and demonstrating ways to overcome them. Rooted in the framework of process metaphysics, this book models metaphysically genuine emergence, paving the way for a comprehensive model of multifarious normative emergences. These normative emergences include phenomena such as function-dysfunction, representational truth and falsity, rational-irrational, ethical-unethical, and others that shape our mental and social landscapes. The discussion extends to the macro-evolutionary culmination of mental processes in a model of reflective consciousness. The book then extends its exploration to the foundational role of mental processes in the emergence of social realities and persons, with language acting as a core element in these emergences. Addressing evolutionary aspects, brain processes, developmental processes, moral normativities, and self-consistency considerations, The Whole Person presents a holistic integration of decades of constructive work.

Semiconductors are at the heart of modern living. Almost everything we do, be it work, travel, communication, or entertainment, all depend on some feature of semiconductor technology. Comprehensive Semiconductor Science and Technology, Second Edition, Three Volume Set captures the breadth of this important field and presents it in a single source to the large audience who study, make, and use semiconductor devices. Written and edited by a truly international team of experts and newly updated to capture key advancements in the field, this work delivers an objective yet cohesive review of the semiconductor world.The work is divided into three sections, fully updated and expanded from the first edition. The first section is concerned with the fundamental physics of semiconductors, showing how the electronic features and the lattice dynamics change drastically when systems vary from bulk to a low-dimensional structure and further to a nanometer size. Throughout this section there is an emphasis on the full understanding of the underlying physics, especially quantum phenomena. The second section deals largely with the transformation of the conceptual framework of solid-state physics into devices and systems, which require the growth of high-purity or doped, bulk and epitaxial materials with low defect density and well-controlled electrical and optical properties. The third section is devoted to design, fabrication and assessment of discrete and integrated semiconductor devices. It will cover the entire spectrum of devices we see all around us, for telecommunications, computing, automation, displays, illumination and consumer electronics.

Biochar for Mitigating Abiotic Stress in Plants provides a unique and leading resource for utilizing biochar to address specific plant health challenges, including osmotic, ionic, and oxidative stress. With a focus on crop yielding plants, the book provides targeted application insights to improve plant health, and resulting crop production. Biochar is a carbon-rich organic substance produced by the pyrolysis of organic materials in the absence or presence of oxygen. It is an organic matter conditioner that can boost carbon sequestration and organic and inorganic pollutant immobilization. It is a crucial method for soil regeneration. Additionally, biochar facilitates increasing mineral supply and soil organic matter, resulting in soils with increased nutritional content. Abiotic stress is characterized as conditions of the environment that inhibit plant growth and produce yields below normal levels. Major abiotic stressors such as high salinity, drought, cold, heat and drought, are reported to result in a decrease of up to 70% in plant survival, biomass production, and yield. Biochar for Mitigating Abiotic Stress in Plants presents important tools toward the identification, treatment and management of a variety of abiotic stressors through the effective and appropriate application of biochar. An important reference for those seeking to apply current knowledge and an inspiration for further research in the area.

Active Peptides for Skin Care is one of the first books on the market that specifically deals with the application of peptides in the field of skin care. The book outlines the basic background to skin and peptides, describes the technical methods for transdermal administration of peptides to exert their effects, and introduces the key issue of quality control methods commonly used to ensure the effectiveness and safety of peptides. The book also covers the mechanism of action and application cases of different efficacies of skin peptides, such as: whitening and spot removal, prolonging and repairing, anti-allergy and soothing, anti-hair loss and growth, improving wrinkles, breast enlargement and slimming, acne repair, eye care, repairing stretch marks, etc.

The Pathology and Imaging of Coronavirus Pneumonia is a comprehensive study of the coronavirus family-related pulmonary diseases, specifically targeting the three subtypes of coronaviruses that have been confirmed to infect humans: SARS, MERS, and COVID-19. It is based on heterogeneous data from imaging and clinical sources, and particularly emphasizes the imaging-based staging diagnostic model rooted in the pathogenic and pathological aspects of clinical staging, thereby aiming to better align with the requirements of evidence-based medicine in clinical diagnosis and treatment.The book provides a comprehensive overview of the pathology and imaging manifestations of coronavirus pneumonia, covering the integrated theories and practical achievements of etiology, epidemiology, pathology, clinical diagnosis, treatment, radiology, cleaning, disinfection, and protection measures commonly used in the imaging department, as well as the prevention and prognosis of SARS, MERS and COVID-19.