Bøger udgivet af Cold Spring Harbor Laboratory Press,U.S.

ext-Generation DNA Sequencing Bioinformatics, Second Edition, provides thorough, plain language introduction to the necessary informatics methods and tools for analyzing NGS data as did the first edition, and provides detailed descriptions of algorithms, strengths and weaknesses of specific tools, pitfalls and alternative methods. Four new chapters in this edition cover: experimental design, sample preparation, and quality assessment of NGS data; Public databases for DNA Sequencing data; De novo transcript assembly; proteogenomics; and emerging sequencing technologies.

Planet Earth can be a dangerous place for all living creatures, including you. You can usually escape from erupting volcanoes and floods. You can protect your body from the blazing Sun and freezing snow. But wherever you live and whatever the weather, you cannot escape GERMS! Enjoy Your Cells is a series of children's books from the acclaimed creative partnership of scientist/author Fran Balkwill and illustrator Mic Rolph. Once again, they use their unique brand of simple but scientifically accurate commentary and exuberantly colorful graphics to take young readers on an entertaining exploration of the amazing, hidden world of cells, proteins, and DNA. It's over ten years since Fran and Mic invented a new way of getting science across to children. Think what extraordinary advances have been made in biology in that time--and how often those discoveries made headlines. Stem cells, cloning, embryo transfer, emerging infections, vaccine developmentELhere in these books are the basic facts behind the public debates. With these books, children will learn to enjoy their cells and current affairs at the same time. And they're getting information that has been written and reviewed by working scientists, so it's completely correct and up-to-date. Readers aged 7 and up will appreciate the stories' lively language and with help, even younger children will enjoy and learn from the jokes and illustrations--no expert required! Discover all the books in the ENJOY YOUR CELLS series, each available in coloring book and full-color formats!

"The focus of Antibodies: A Laboratory Manual, 2nd Edition, will be unchanged from the original edition by Ed Harlow and David Lane and will cover both the production and use of antibodies in a way that is accessible to the nonimmunologist. The emphasis will be on contemporary, essential antibody-based methods that are tried, true, necessary, and u

Cold Spring Harbor Laboratory Press presents the ultimate research notebook, the perfect tool for the student as well as the professional researcher. With 50 carbonless, duplicate pages, and table of contents, the paperback edition can help you organize the most hectic lab schedule. Each notebook includes seven pages of essential reference tables and charts, information on common solutions, and measurement conversion factors selected from Cold Spring Harbor Laboratory Press manuals. This is the most functional, economical, and professional lab resource available.

Andy O'Hara, a post-doctoral researcher in a London cancer research institute, agrees to help an attractive colleague, Gina, who is collaborating with a pharmaceutical company. She is working on a virus-based vaccine but has discovered the company is planning a clinical trial of the vaccine in Africa without preliminary animal tests. Andy gets a tip-off that Gina's corporate collaborator has a shady past, but also discovers a scientific reason why the vaccine may be doomed to failure. As this excerpt begins, Andy and his friend Christine have helped Gina set up an illicit mouse experiment in their own animal facility, a move that could end all their careers if discovered.

The methods found here are drawn from such popular manuals as "Proteins and Proteomics: A Laboratory Manual" and "Purifying Proteins for Proteomics: A Laboratory Manual." This volume contains an essential collection of purification methods using gel electrophoresis and column chromatography.

This engrossing biography by one of molecular biology's foremost scholars reveals the remarkable evolution of Francis Crick's scientific career and insights into his personal life, from his early studies in biophysics, to the discovery of the structure of DNA, to his later work in neuroscience and the nature of consciousness.

"Single Molecule Techniques" is the first laboratory manual to take researchers who know nothing about single-molecule analyses to the point where they can successfully design and execute appropriate experiments. Techniques range from in vivo and in vitro fluorescent-based methods to the use of atomic force microscopy.

World-renowned in the fields of population genetics, bacterial genomics, paleontology, human genetics, and developmental biology, the authors have elegantly synthesized molecular biology and evolutionary biology to produce a thoroughly integrated and current text. This new (textbook) is among the best.--"Nature." Full color.

Derived from the acclaimed online "WormAtlas," C. elegans Atlas is a large-format, full-color atlas of the hermaphroditic form of the model organism C. elegans, known affectionately as "the worm" by workers in the field. Prepared by the editors of the WormAtlas Consortium, David H. Hall and Zeynep F. Altun, this book combines explanatory text with copious, labeled, color illustrations and electron micrographs of the major body systems of C. elegans. Also included are electron microscopy cross sections of the worm. This laboratory reference is essential for the working worm biologist, at the bench and at the microscope, and provides a superb companion to the C. elegans II monograph. It is also a valuable tool for investigators in the fields of developmental biology, neurobiology, reproductive biology, gene expression, and molecular biology.

Unavailable in the U.S. for many years, Horace Judson's remarkable lay history of molecular biology is now published in a new, expanded edition. The author has added new material on some of the principal figures involved, particularly Rosalind Franklin. Also included are a new Forward and an Afterword which sketches the further development of molecular biology into the era of recombinant DNA. No one active in current molecular genetics can fail to be informed and entertained by this extraordinary account of how it all began. Also highly recommended for students and interested lay people.

Beneath your skin there are millions and millions of cells working together to make eveything that is you. This series offers children a simple but scientifically accurate commentary to take them on an exploration of the amazing, hidden world of cells, proteins, and DNA.