Bøger udgivet af BOD THIRD PARTY TITLES

Biomimetics is an innovative form of technology that emulates, imitates, or mimics nature in order to improve human lives by creating desirable solutions. It is the study of nature and natural phenomena in an attempt to understand its laws, principles, and underlying mechanisms, to obtain ideas from nature, and to apply concepts that may benefit science, engineering, pharmacy, dentistry, and medicine. Smart/intelligent biomaterials for tissue engineering and regenerative medicine are fine examples of biomimetics. Yet, biomimicry can go above and beyond the simplistic inspiration and use of natural properties as the basis for the innovation of new products. It bridges the gap between the lab and the industry via the intra-disciplinary design and formulation of functional solutions combining knowledge, methods, techniques, and advances in the fields of chemistry, biology, architecture, engineering, medicine, pharmaceutics, dentistry, and biomedical engineering. Three-dimensional printing, self-healing nanocoatings, hydrogels, bio-mechanical carbon nanotubes, stimuli-sensitive and -responsive cell/drug delivery systems, and robotics are some of the topics covered in this book. In a simplified style, the book provides interested readers with a practical reference approaching biomimetics and biomimicry from a realistic and translational perspective, discussing problems and offering solutions and including studies ranging from basics to the clinic to scale-up and industrial or go-to-market obstacles. Through Biomimetics - Bridging the Gap, you'll quickly discover that biomimicry is more than just looking at a silkworm (silk is one of the first examples in history) or at the shape of a flower, a damselfly, or even a humpback whale and becoming re-inspired. Biomimicry is an intra-/multi-disciplinary methodology and technological-oriented approach presently employed by the most innovative organizations on this planet.

This book collates up-to-date information about Candida and candidiasis, covering the following topics: diversity and genetic structure of the genus Candida, invasion biology of candidiasis, pathogenicity, drug resistance, antifungal susceptibility, antifungal-resistant Candida strains, antifungal-resistant genes among resistant isolates, molecular mechanisms of antifungal resistance, diagnosis and targeted therapy of candidiasis, cytotoxicity, biofilms, Candida albicans and non-C. albicans, Covid-19 patients and proteomics, pustules, systemic therapies, topical therapies, new effective compounds against Candida spp. cutaneous candidiasis, oropharyngeal candidiasis, oesophageal candidiasis, vulvovaginal candidiasis, intestinal candidiasis, invasive candidiasis, molecular methods in the diagnosis of Candida strains, host-pathogen interactions, interactions between Candida and cancer, antifungal drug discovery, natural compounds effective against Candida strains, and novel active compounds for candidiasis treatment.

Aflatoxins are produced by fungi on agricultural crops. They contaminate foods and feeds worldwide and are a threat to humans and animals. They can occur at any stage from pre- to post-harvest, including transportation and storage. This book discusses aflatoxins with chapters on occurrence and prevalence, contamination exposure, toxicology and control in foods and feeds, immunosuppressive actions, hazards and regulations, detection methods, effects of climate change, novel detoxification strategies, and legislations.

Mutations in the BRCA1/2 genes are the most common cause of hereditary breast and ovarian cancer (HBOC), and HBOC is an autosomal dominant cancer predisposition syndrome. Individuals with HBOC have a high risk for breast and ovarian cancers and a moderate risk for other cancers, such as prostate, pancreatic, melanoma, and fallopian tube cancers. The goal of screening individuals at high risk of familial cancer is either prevention (such as a change in lifestyle or diet) or early detection of cancer. The identification of BRCA mutation carriers is important, since increased surveillance, drug therapy, and prophylactic surgery can reduce cancer-related morbidity and mortality. In recent years, there has been substantial development in BRCA-associated hereditary breast and/or breast-ovarian cancer research and its clinical applications. In this context, this book consolidates the recent advances in BRCA-related cancer biology and therapeutics, covering a wide spectrum of interrelated topics. Chapters cover a wide range of topics, such as BRCA discovery, BRCA structure and function, BRCA-associated cancers, BRCA genetic testing and counselling, and more. This book is a valuable resource not only for medical and allied health students but also for researchers, clinical and nurse geneticists, genetic counselors, and physician assistants.

CRISPR technology has been extensively used in vitro and in vivo as a tool in basic research for genetic editing (e.g., genome encoding, silencing, enhancing, and modification). Although there are many technical and ethical challenges to overcome, such as off-target effects, delivery tool selection, and safety concerns, scientists are working to improve this technology. CRISPR technology is promising for practical applications as well as for laboratory work and basic research. Currently, CRISPR is being used successfully in microbial detection, disease diagnosis, and manufacturing of agricultural products, food, industrial products, and medicinal products. The development of medicinal products using CRISPR will open a new era for human therapeutics and may bring hope for the recovery of ill patients. This book provides a comprehensive overview of CRISPR technology. It examines its discovery, improvement, and implications, explores its technology and applications, and discusses perspectives and challenges.

Lifestyle-related diseases are caused by an unbalanced diet and irregular, undesirable lifestyle, leading to a condition called metabolic syndrome. Rather like dominoes falling, these diseases develop one after another. Owing to changes in dietary habits and working environments, the incidence of lifestyle-related diseases, obesity, and metabolic syndrome is increasing globally, resulting in a serious social problem that needs to be solved. This book deals with recent studies on lifestyle-related diseases and metabolic syndrome, and the following three topics are discussed: (1) characteristics of metabolic syndrome and lifestyle-related diseases; (2) the relationship between metabolic syndrome and several diseases; and (3) effective interventions to prevent lifestyle-related diseases. This book provides new ideas for the treatment and prevention of metabolic syndrome and lifestyle-related diseases.

Human activities cause the degradation of innumerable ecosystems, including forests. The degradation of forests leads to far-reaching nutrient cycle changes throughout all environments. Reversible or irreversible degradation processes cause declines in an ecosystem's ability to self-regulate. Reversible processes decrease native forest biodiversity while preserving the ecosystem's abiotic components, whereas irreversible processes alter the character of the potential natural vegetation. This book discusses forest degradation in three sections on general, climatic, and land-use degradative effects.

The commonness and complexity of COPD necessitate rapid communication of significant new knowledge of the disease. This book provides a platform for sharing new notions in scientific research as well as contemporary clinical best practices. It combines noetic theoretical concepts with the ontic practical management of COPD. Epistemological concepts explored in this book include contextualization in the evaluation and treatment of COPD, as well as the latest in the basic science of airway inflammation, "omics" research, and delivery therapeutics. Practical topics addressed include early detection and alleviation of COPD exacerbation, pulmonary rehabilitation, and identifying phenotypes or treatable traits to optimize inhaled therapy.

Catfish, one of the largest groups of freshwater fishes, are not only important ornamentals and sport fishing and research animals but also an important source of protein. This book compiles current research on this species, providing information on its production methods and uses.

The first roundworm identified in humans was Ascaris, described by Linnaeus in 1758. Rudolphi's 1808 classification was the first to describe the Nematoidea. With the development of new molecular techniques, classification and phylogenetic research have also frequently changed; in 2019 a new classification, the phylum Nematoda, was created based on evolutionary relationships, developmental and morphological features and recent molecular evidence. Nematodes, which include hookworms, whipworms, threadworms, and soil-borne worms, are one of the oldest disease-causing creatures, dating back to Ancient Greek, Roman and Mesopotamian civilizations. Most commonly affecting children and women, the disease causes developmental disorders, cognitive impairment and death, with symptoms primarily affecting the organs they inhabit. In this book, the historical background, biology, transmission routes and geographical distribution of some roundworms affecting human health are discussed.

Melatonin is a powerful hormone and antioxidant with numerous effects on metabolism and human health. Available as a dietary supplement for many years, it is one of the most popular over-the-counter alternative medicines available. Featuring contributions from researchers investigating the role of melatonin in various diseases and physiological conditions, this comprehensive book offers a wide range of expert reviews on the synthesis, regulation, and physiological effects of melatonin as well as its role in various diseases.

Panic disorder is often confused with elevations of anxiety and what is often described as "anxiety attacks." However, panic is qualitatively different from these phenomena. Panic disorders or panic attacks are intense and usually brief episodes that have often come upon the sufferer as an extreme dread and fear of annihilation. Panic attacks are startling and often produce a sense of impending doom and fear of imminent disaster. They are associated with heart palpitations, dizziness, tingling of extremities, disorientation, and the urge to flee the present environment. During a panic attack, it is not unusual for the sufferer to act in ways that seem completely irrational and beyond the realm of sanity. Imagine sitting quietly in a darkened room and being intensely engrossed in a book that you cannot put down. Suddenly you feel someone's hands grasp your neck and begin choking you. That level of startled and life-threatening fear is like what many report during a panic attack. It is difficult to know what causes this disorder. In many cases, sufferers report having endured traumatic experiences, especially in childhood. However, in an equal percentage of cases, there is no prior trauma history, and the origins of the panic disorder are unknown, although they do tend to run in families. This book elucidates the nature of panic, the factors that contribute to the disorder, and describes psychological, physiological, and medical interventions that have been useful in ameliorating the suffering brought on by panic attacks.

Safe drinking water, sanitation, and hygiene are crucial to human health and wellbeing. These factors are a prerequisite to health since they play a crucial role in preventing the transmission of numerous waterborne pathogens and chemical contaminants. Another important factor that can affect people's health is air pollution. Special attention needs to be paid to developing countries, as these factors not only affect human health but also contribute to livelihoods, school attendance, and dignity and help create resilient communities living in healthy environments. This book provides insights into different aspects of hygiene, sanitation, water, and air pollution and their potential correlation with infectious diseases and human health. It also addresses important challenges and opportunities for improvement in developing countries. These are priority areas in which the world's leading health and humanitarian organizations, such as the WHO and UNICEF, are working intensively.

Updates on Software Usability is a collection of high-quality contributions for developers and non-developers alike. Beyond the preliminaries, the book is organized into two other parts: "Designing for Usability" and "Testing for Usability". The chapters in the second section, "Designing for Usability", offer valuable insights and practical guidance to take into account during the early stages of product conception and development. On the other hand, the chapters in the third section, "Testing for Usability", reflect and formalize software usability's evaluation and validation processes. These two complementary views on the subject make this book a balanced and comprehensive volume, which the reader will undoubtedly find both interesting and useful.

According to the World Health Organization, nearly 80% of people with epilepsy live in low- and middle-income countries and could live seizure-free if properly diagnosed and treated. Among the structural and genetic triggers that may lead to epilepsy are head trauma, abnormal synaptic connectivity, receptor subunits anomalies, and atypical ionic channel function. Developing brains are specifically susceptible to seizures for many reasons, for example, the presence of enhanced excitation due to the early production of excitatory neurotransmitters, and the fact that the inhibitory neurotransmitter GABA causes excitation early in life. These studies help to clarify why the very young brain is exceptionally prone to seizures. The chapters presented in this book describe how structural, genetic, infectious, and metabolic abnormalities can lead to epileptogenesis. Nevertheless, many underlying disease mechanisms that can lead to epilepsy remain unknown.

The purpose of this book is to present some uses of the Kalman filter (KF) in engineering activities that can produce a robust and technically acceptable result while keeping as close as possible to the optimal (most accurate) solution. KF sub-optimization is often required, due to the realities of implementation and real-life operational conditions. The book brings together the experiences of specialists from different engineering areas using the KF in their practice.

In many parts of the world, the use of antibiotics in food-producing animals is partially or completely banned. This has led to increased research to develop alternatives to antibiotic growth promoters (AGPs). Some of these alternatives include prebiotics, probiotics, and phytoadditives. This book focuses on probiotics, which are the most feasible option to replace AGPs because they directly modulate the gut microbiota and improve gut absorption, which ultimately accelerates growth and production. The book provides recent updates on the use of probiotics in farm animals including poultry, fish, and ruminants as well as pet animals.

It is well known that the theory of dynamical systems is an essential mathematical tool in the analysis of various real-world processes and phenomena that evolve over time. Different aspects of this rich field of research are evolving all the time, including new theoretical results for qualitative investigation as well as fast numerical techniques for approximate solution. The book provides an overview of the current state of the art in this fascinating and critically important field of pure and applied mathematics, presenting recent developments in theory, modeling, algorithms, and applications.

This book provides a comprehensive overview of light-emitting diodes (LEDs). Chapters discuss micro-LEDs, nano-LEDs, high-power LEDs, and advancements in LED technology. It is a useful resource for a wide range of readers, including scientists, engineers, graduate students, postdoctoral fellows, and scientific professionals working in LEDs.

Aridity is the imbalance between long-term average water supply and long-term average water demand. Arid environments cover more than one-third of the world's land area and represent the most common habitat on Earth after the oceans. Aridity poses a threat to the environment and the economy, and to security, development, food security, and social life around the world. The causes of increased aridity are complex and are thought to be both natural and man-made. The causes of drought include such factors as climate change, population growth, soil erosion, inappropriate irrigation, poor farming methods, soil, water, and groundwater contamination, urbanization, deforestation, improper water management, and desertification of arid and semi-arid zones. This book contains valuable scientific studies on such aspects of aridity as surface and groundwater management, land use, and agricultural applications. Case studies from different geographies and planets are included.

Nanoclays, currently regarded as nanomaterials with sustainable characteristics, have a variety of intriguing properties. Clays come in a wide variety of nanoscale morphologies and are chemically made up of hydrated aluminum silicates with varying amounts of additional elements like magnesium, iron, calcium, and potassium. Given their properties and accessibility in a variety of nanoscale morphologies, nanoclays are well suited for a broad range of possible uses. To create nanocomposite materials with specific characteristics and particular functionalities, composites based on polymers and clay nanoparticles have been thoroughly investigated. Recent research has demonstrated the use of polymer/nanoclay systems in the antibacterial coating, smart food packaging, drug delivery systems, tissue engineering, reinforced bioplastics, and flame-retardant materials. However, further study is still required to clarify their structure-property relationships. Hybrid organic/inorganic clays generate a wide number of perspectives, nanoarchitectures and materials. In general, the utilization of nanoclays can remove the typical cost barrier associated with nanotechnologies and provide new, sustainable pathways. The contributions that describe recent research in nanoclay science for technological applications are collected in this edited volume.

This book presents an overview of Industry 4.0 (IR4.0) technologies including the Internet of Things (IoT), big data, data mining, deep learning, machine learning, Artificial Intelligence (AI), and cloud/edge computing. It also provides detailed insight into the impact of cutting-edge technologies such as the Internet of Services (IoS), innovative sensing strategies, and cyber-physical systems on IR4.0 as well as data-driven, real-time detection, and condition monitoring applications.

This book provides a comprehensive overview of non-governmental organizations (NGOs), including their development, structure, marketing, and challenges. It is divided into two sections: "Management Aspects of NGOs in the Area of Development, Marketing and Sourcing", and "Case Studies of NGOs". Chapters discuss the development of NGOs and present case studies of NGOs in various countries, including Ethiopia, Bangladesh, South Africa, and others. They also address such topics as NGOs in the healthcare sector, the effect of the COVID-19 pandemic on the humanitarian supply chain, and how NGOs can protect and preserve cultural heritage.

Recent Updates in Eating Disorders raises recent relevant issues about eating disorders and obesity that have led us to speak of an 'eating disorder society', especially among adolescents who are at the most vulnerable stage of life. It is important not only to be aware of the behaviours that occur before the emergence of an eating disorder, but also, from a clinical perspective, to talk about diagnostic criteria. It is also important to specify, as accurately as possible, the severity criteria and the presence of comorbidity, in order to establish better protocols for therapeutic action. We also address the issue of social media networks and their influence on the development of eating disorders (and many other problems). While this work is neither exhaustive nor extensive, we nevertheless hope it will be of interest and will open up further lines of study and research in the near future.

The book includes important contributions that discuss state-of-the-art techniques and technologies for monitoring lentic and lotic water environments. It includes contributions that deepen and integrate the knowledge of the impacts and pressures of surrounding environments in the monitoring techniques of aquatic environments. Furthermore, the book presents studies relating to the management of inland waters and related indicators to identify the most common pollution problems.

The intermittent nature of solar energy sources is the greatest challenge to the broad acceptance of this technology. The storage of thermal energy presents a workable option for addressing this issue. When it comes to the storage of thermal energy, latent heat storage units (LHSU) that make use of phase change materials (PCMs) are more desirable than sensible heat storage. In the context of a large increase in the demand for energy, PCMs are an essential class of thermal energy storage materials that contribute to the sustainable growth of both the economy and society. It stores large amounts of heat in the form of latent heat at a constant temperature. This promising technique has already been applied with great success in a variety of applications like solar appliances, buildings, battery thermal management, electronic cooling, waste heat recovery systems, textiles, and more. This book presents an in-depth discussion on PCMs, the current state of PCM technology, and a detailed description of their prospective applications.

We are living in a critical time, both for humanity and the planet, which has led us to look for more sustainable formulas to interact with the environment. One of the important changes in the design and operation of chemical processes is the search for environmentally friendly technologies. Supercritical carbon dioxide has been revealed as a promising environmentally friendly solvent that is energy efficient, selective and capable of reducing waste, making it a promising alternative to conventional organic solvents. However, reliable and versatile mathematical models of phase equilibrium thermodynamics are needed for the use of supercritical carbon dioxide in process design and viability studies. This book reviews experimental procedures for obtaining high-pressure phase equilibria data and describes the phase diagrams of binary mixtures and some thermodynamic models capable of determining the conditions of phase equilibria at high pressures. These concepts are applied to the components of the transesterification reaction of rac-2-pentanol with a vinyl ester, which is important in the pharmaceutical industry because (S)-2-pentanol can be obtained as a reaction product. This product is a key intermediate in the synthesis of drugs against Alzheimer's disease.

Recent Advances, New Perspectives and Applications in the Treatment of Ovarian Cancer is a review of interesting and clinically important advances in the tumor biology and treatment of ovarian cancer. Major aspects of scientific progress in the treatment of ovarian cancer are covered, focusing on new knowledge due to advances in molecular techniques, understanding of tumor biology and innovative new treatment options. An interesting collection of innovations in the treatment of ovarian cancer and opinions from specialists in this field from around the world are brought together in this book.

Despite technological advancements, the human operator is still the most important part of any production system. To increase productivity, quality, and effectiveness within production systems, ergonomics, the study of people's efficiency in their working environment, is crucial. Ergonomics involves three pillars: physical, organizational, and cognitive. In today's technologically competitive production environment, physical ergonomics is evolving into the automation of repetitive manual tasks, and manual handling involving logistics and transportation is being improved by new digital technologies. Organizational ergonomics is moving towards studying the requirements of hybrid production systems where humans and machines are becoming more integrated. Virtual models can facilitate timely interactions and enhance perception, cyber-physical systems are developing new ways for people to interact with machines, the use of augmented reality tools will lessen mental stress, and data exchange between departments is expected to enhance cognitive ergonomics. This book discusses recent advances in each of the three pillars of ergonomics.

Molecular docking is a widely used bioinformatics method in biology, medicine, and biochemistry. This method, which can model interactions between different receptors and their various ligands at the molecular level, can represent intermolecular interactions at an unprecedented resolution that may not be achieved by classical experimental approaches. This book describes different aspects of this method that can reveal the intermolecular biochemical and biophysical interactions and the affinities of partner molecules to each other. It is designed for academics, students, and professionals interested in this technique.