Bøger udgivet af Academic Press

This volume reviews the current research in Chemokine Receptors and their role in physiological processes in the body, as well as their role in different pathological conditions. Chemokine Receptors are important for the migration of different types of cells, including immune cells to lymphoid organs and non-lymphoid organs thanks to the interaction with chemokines. The presence of different chemokine receptors on the cells' surface was studied in normal states and diseases, some of them correlating with migration of subsets that play pro-disease roles or other help controlling the condition. Currently, state-of-the-art technology is helping researchers to better identify gene and protein expression of chemokine receptors at the single cell level. This large new data reveals the complexity of co-expression of various markers in the same cells and as well among different types of cells. Moreover, chemokine receptors are also helpful to identify different stages among subsets, and their correlation with better or worst responses in disease. Finally, treatments designed to inhibit or to block chemokine receptors are designed and tested at the preclinical and clinical level with different results. Here, we focus on the main chemokine receptors described in the current literature that play a role in health and diseases such as infections, autoimmune disorders, and cancer.

Peptide Chemical Tools for Modulating Biology, Volume 698 in the esteemed Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting topics on Peptide tools that target telomere maintenance, Molecular Design of Peptide Therapeutics, Sulfonyl peptide tools for modulating biology, Peptide tools for targeting the Crk/CrkL-p130Cas axis, Quorum sensing peptide tools, In vivo stability and BBB penetration of peptide tools, and Oligo-benzamide-based peptide mimicking tools for modulating biology.

Advanced Calculus for Mathematical Modeling in Engineering and Physics: With Discrete and Numerical Analogies introduces the principles and methods of advanced calculus for mathematical modeling through a balance of theory and application using a state space approach with elementary functional analysis. This framework facilitates a deeper understanding of the nature of mathematical models, and of the behavior of their solutions. The work provides a variety of advanced calculus models for mathematical, physical science, and engineering audiences, with discussions on how calculus-based models and their discrete analogies are generated. This valuable textbook offers scientific computations driven by Octave/MATLAB script.

As Bayesian techniques become more common across a variety of fields, it becomes important for experts in those fields to understand those methods. An Introductory Handbook of Bayesian Thinking brings Bayesian thinking and methods to a wide audience beyond the mathematical sciences. Appropriate for students with some background in calculus and introductory statistics, particularly for nonstatisticians with a sufficient mathematical background, the text provides a gentle introduction to Bayesian ideas with a wide array of supporting examples from a variety of fields.

Cutting Edge Artificial Intelligence, Spatial Transcriptomics and Proteomics Approaches to Analyze Cancer, Volume 163 in the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting interesting topics on the Impact of thermal processing on food flavonoids, Bioinformatics and bioactive peptides from foods: does it work together?, Food off-flavor volatiles generation, characterization and advances in novel strategies for mitigating off-flavor perception, Innovations in Food Packaging for a Sustainable and Circular economy, Upcycling of seafood side streams for circularity, Edible insects in foods, Effect of novel food processing technologies on Bacillus cereus spores, and more.

Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

Advances in Rhizostomeaen Jellyfish Research, Volume 97 in the Advances in Marine Biology series, the latest release in this serial that highlights new advances in the field, includes comprehensive chapters written by an international board of authors.

Vertebrate Pattern Formation, Volume 159 in the Current Topics in Developmental Biology series, highlights advances in the field, with this volume presenting interesting chapters on timely topics, including Hox genes patterning the vertebrate body, Endodermal patterning, The use of organoids/gastruloids to understand development, Cell shape and movements controlling development, Neural crest and placodes in vertebrate development, Patterning of the neural tube, Non-canonical Wnt signaling in axial extension, The control of transitions along the main body axis, Emergence of a left-right symmetric body plan in vertebrate embryos, Formation of the vascular system, Generation of patterns in the paraxial mesoderm, and more.

Advances in Cancer Research, Volume 162 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors

Glycation, Volume 125 in the Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

Basic Neurochemistry: Principles of Molecular, Cellular, and Medical Neurobiology, Ninth Edition is a classic advanced neurochemistry and neurobiology textbook that has a renewed focus on clinical applications. The early chapters focus on fundamental membrane chemistry, cellular signaling, and development of the nervous system. Later chapters cover cell injury and inflammation, neurodegenerative diseases, sensory transduction, and neural processing/behavior. By understanding mechanisms at the molecular and systems level, scientists can develop new pharmacotherapies to treat diseases such as Alzheimer's Disease, Parkinson's Disease, Multiple Sclerosis as well as neuropsychiatric diseases (e.g., schizophrenia, depression, pain, addictions). This book provides a foundation of all key principles of neurochemistry and neurobiology--within the context of human diseases--for advanced students and graduate students in neuroscience, biomedical sciences, as well as clinical neuroscientists and neurologists.

This reference, written by leading authorities in the field, gives basic theory, implementation details, advanced research, and applications of RF and microwave in healthcare and biosensing. It first provides a solid understanding of the fundamentals with coverage of the basics of microwave engineering and the interaction between electromagnetic waves and biomaterials. It then presents the state-of-the-art development in microwave biosensing, implantable devices -including applications of microwave technology for sensing biological tissues - and medical diagnosis, along with applications involving remote patient monitoring. this book is an ideal reference for RF and microwave engineer working on, or thinking of working on, the applications of RF and Microwave technology in medicine and biology. Learn: The fundamentals of RF and microwave engineering in healthcare and biosensing How to combine biological and medical aspects of the field with underlying engineering concepts How to implement microwave biosensing for material characterization and cancer diagnosis Applications and functioning of wireless implantable biomedical devices and microwave non-contact biomedical radars How to combine devices, systems, and methods for new practical applications

Many enterprises currently are suffering from problems in IT management and quality because they are locked in by a monopolist vendor, with resultant rising TCO and technical problems. However, in a growing number of enterprises there is overall optimism, because Linux and Open Source Software are proving to be a way out of the business dilemma. And now, CEOs have started asking their CIOs for more information about Linux.

The publication of the extensive 7-volume work Comprehensive Molecular Insect Science provided library customers and their end-users with a complete reference encompassing important developments and achievements in modern insect science, including reviews on the ecdysone receptor, lipocalins, and bacterial toxins. One of the most popular areas in entomology is control, and this derivative work, Insect Control, taps into a previously unapproached market - the end user who desires to purchase a comprehensive yet affordable work on important aspects of this topic. Contents will include timeless articles covering insect growth- and development-disrupting insecticides, mechanisms and use of Bacillus thuringiensis, biology and genomics of polydnaviruses, pheromones: function and use in insect control, and more. New summaries for each chapter will give an overview of developments in the related article since its original publication.

Fundamentals of Quantum Chemistry is an introduction to the principles of quantum mechanics needed in physical chemistry. Mathematical tools are presented and developed as needed and only basic calculus, chemistry, and physics is assumed. Applications include atomic and molecular structure, spectroscopy, alpha decay, tunneling, and superconductivity. New edition includes sections on perturbation theory, orbital symmetry of diatomic molecules, the Huckel MO method and Woodward/Hoffman rules as well as a new chapter on SCF and Hartree-Fock methods.

Computational Methods in Engineering brings to light the numerous uses of numerical methods in engineering. It clearly explains the application of these methods mathematically and practically, emphasizing programming aspects when appropriate. By approaching the cross-disciplinary topic of numerical methods with a flexible approach, Computational Methods in Engineering encourages a well-rounded understanding of the subject. This book's teaching goes beyond the text--detailed exercises (with solutions), real examples of numerical methods in real engineering practices, flowcharts, and MATLAB codes all help you learn the methods directly in the medium that suits you best.

As the biomedical engineering field expands throughout the world, clinical engineers play an evermore-important role as translators between the medical, engineering, and business professions. They influence procedure and policy at research facilities, universities, as well as private and government agencies including the Food and Drug Administration and the World Health Organization. The profession of clinical engineering continues to seek its place amidst the myriad of professionals that comprise the health care field. The Clinical Engineering Handbook meets a long felt need for a comprehensive book on all aspects of clinical engineering that is a suitable reference in hospitals, classrooms, workshops, and governmental and non-governmental organization. The Handbook's thirteen sections address the following areas: Clinical Engineering; Models of Clinical Engineering Practice; Technology Management; Safety Education and Training; Design, Manufacture, and Evaluation and Control of Medical Devices; Utilization and Service of Medical Devices; Information Technology; and Professionalism and Ethics. The Clinical Engineering Handbook provides the reader with prospects for the future of clinical engineering as well as guidelines and standards for best practice around the world. From telemedicine and IT issues, to sanitation and disaster planning, it brings together all the important aspects of clinical engineering.

Advances in Imaging and Electron Physics, Volume 218 merges two long-running serials, Advances in Electronics and Electron Physics and Advances in Optical and Electron Microscopy. The series features articles on the physics of electron devices (especially semiconductor devices), particle optics at high and low energies, microlithography, image science, digital image processing, electromagnetic wave propagation, electron microscopy and the computing methods used in all these domains. Specific chapters in this release cover Phase retrieval methods applied to coherent imaging, X-ray phase-contrast imaging: a broad overview of some fundamentals, Graphene and borophene as nanoscopic materials for electronics - with review of the physics, and more.

Domino Effect: Its Prediction and Prevention, Volume Five in the Methods in Chemical Process Safety series, focuses on the process of learning from experience, including elements of process safety management, human factors in the chemical process industries, and the regulation of chemical process safety, including current approaches. Users will find this book to be an informative tool and user manual for process safety for a variety of professionals. This new release focuses on Domino effect - Case histories and accident statistics, the state-of-the-art in domino effect modeling, Fire Driven Domino Effect, Mitigation of Domino Effect, and much more.

This book gives a review of the principles, methods and techniques of important and emerging research topics and technologies in Channel Coding, including theory, algorithms, and applications. Edited by leading people in the field who, through their reputation, have been able to commission experts to write on a particular topic. With this reference source you will: Quickly grasp a new area of research Understand the underlying principles of a topic and its applications Ascertain how a topic relates to other areas and learn of the research issues yet to be resolved

Introduction to Optimum Design, Fifth Edition is the most widely used textbook in engineering optimization and optimum design courses. It is intended for use in a first course on engineering design and optimization at the undergraduate or graduate level within engineering departments of all disciplines, but primarily within mechanical, aerospace and civil engineering. The basic approach of the text presents an organized approach to engineering design optimization in a rigorous yet simplified manner, illustrating various concepts and procedures with simple examples and demonstrating their applicability to engineering design problems. Formulation of a design problem as an optimization problem is emphasized and illustrated throughout the text. Excel and MATLAB are featured as learning and teaching aids. This new edition has been enhanced with new or expanded content in such areas as reliability-based optimization, metamodeling, design of experiments, robust design, nature-inspired metaheuristic search methods, and combinatorial optimizaton.

In many plants, vibration and noise problems occur due to fluid flow, which can greatly disrupt smooth plant operations. These flow-related phenomena are called flow-induced vibration. This book explains how and why such vibrations happen and provides hints and tips on how to avoid them in future plant design. The world-leading author team doesn't assume prior knowledge of mathematical methods and provides the reader with information on the basics of modeling. The book includes several practical examples and thorough explanations of the structure, the evaluation method and the mechanisms to aid understanding of flow-induced vibrations.

International Review of Movement Disorders series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

This in-depth, detailed reference presents for the first time a comprehensive treatment of recent advances in optical performance monitoring. Written by leading experts in the field, the book provides an overview of recent developments in the area and the role of OPM in future optical systems and networks. Detailed discussions of various advanced techniques are provided to illustrate their principles. FEATURES: Presents the principles and applications of advanced OPM techniques, together with a comparative evaluation of their effectiveness in monitoring individual parameters, such as optical signal-to-noise ratio, chromatic dispersion, and polarization mode dispersion Explains the principles of the various advanced optical signal processing techniques and their applications in OPM Examines the role and applications of OPM in optical networks, including optical transport networks, coherent optical systems, and long-haul optical transmission systems Discusses the current approaches of OPM in the global standard SDH/SONET This book is ideal for technical professionals and researchers who want to understand and evaluate advanced techniques in OPM and their impact on the practical design of next-generation optical systems and networks.

Fracture Mechanics covers classical and modern methods and introduce new/unique techniques, making this text an important resource for anyone involved in the study or application of fracture mechanics. Using insights from leading experts in fracture mechanics, it provides new approaches and new applications to advance the understanding of crack initiation and propagation. With a concise and easily understood mathematical treatment of crack tip fields, this book provides the basis for applying fracture mechanics in solving practical problems. It features a unique coverage of bi-material interfacial cracks, with applications to commercially important areas of composite materials, layered structures, and microelectronic packaging. A full chapter is devoted to the cohesive zone model approach, which has been extensively used in recent years to simulate crack propagation. A unified discussion of fracture criteria involving nonlinear/plastic deformations is also provided. The book is an invaluable resource for mechanical, aerospace, civil, and biomedical engineers in the field of mechanics as well as for graduate students and researchers studying mechanics.

Distillation: Operation and Applications--winner of the 2015 PROSE Award in Chemistry & Physics from the Association of American Publishers--is a single source of authoritative information on all aspects of the theory and practice of modern distillation, suitable for advanced students and professionals working in a laboratory, industrial plants, or a managerial capacity. It addresses the most important and current research on industrial distillation, including all steps in process design (feasibility study, modeling, and experimental validation), together with operation and control aspects. This volume features an extra focus on distillation applications.

Wildlife Demography compiles the multitude of available estimation techniques based on sex and age data, and presents these varying techniques in one organized, unified volume. Designed to guide researchers to the most appropriate estimator based upon their particular data set and the desired level of study precision, this book provides quantitative consideration, statistical models, estimator variance, assumptions and examples of use. The authors focus on estimation techniques using sex and age ratios because this data is relatively easy to collect and commonly used by wildlife management.

Numerical Methods using MATLAB, 3e, is an extensive reference offering hundreds of useful and important numerical algorithms that can be implemented into MATLAB for a graphical interpretation to help researchers analyze a particular outcome. Many worked examples are given together with exercises and solutions to illustrate how numerical methods can be used to study problems that have applications in the biosciences, chaos, optimization, engineering and science across the board.

This is a study of the evolution of the principles and techniques of cranial surgery from Hippocrates to the nineteenth century. The methods of conveying information by text and image are considered.

Advances in the Study of Behavior was initiated over 40 years ago to serve the increasing number of scientists engaged in the study of animal behavior. That number is still expanding. This volume makes another important "contribution to the development of the field" by presenting theoretical ideas and research to those studying animal behavior and to their colleagues in neighboring fields. Advances in the Study of Behavior is now available online at ScienceDirect full-text online from volume 30 onward.