Bøger af Vivek Mishra

Nanotherapeutics for Inflammatory Arthritis: Design, Diagnosis, and Treatment highlights nanobiotechnology and its therapeutic applications in the field of inflammatory arthritis, the interaction of nanomaterials in the biological systems, and clinical development of nanomedicines. It also covers the discovery of personalized therapeutics, diagnostics, and nanoparticular delivery systems, the role of bioinformatics nanobiotechnology in personalized oncology. The use of nanosensors for the detection and current challenges in the development of personalized medicine is explained including recent nanotechnology-based strategies.Features: Covers all the fundamental information about nanotechnology and inflammatory arthritis. Highlights the interaction of nanomaterials in the biological systems, and the clinical development of nanomedicines for inflammatory arthritis. Explores discovery of personalized therapeutics, diagnostics, and nanoparticle delivery systems. Reviews current challenges in the development of personalized medicine as well as translation of nanomedicine with combination therapy. Discusses toxicology of using nanomedicines and the risks associated with the use of these nanomedicines. This book is aimed at researchers and professionals in nanotechnology, biomaterial, drug delivery, and inflammatory arthritis.

The United Nations has always been held in high esteem in India, particularly during the Nehru years when an internationally minded Prime Minister ensured that India's voice would be heard in global debates on security, development, human rights and race relations. The evolving views of all Indian Governments on these matters were reflected in the opening statements made by heads of the Indian delegation, usually the Prime Minister or Foreign Minister, at the September General Assembly Session of the United Nations. This volume brings together these opening statements from 1945 onwards and presents in effect a history of India's international stance on issues of national and global concern. It is an invaluable resource for any student of modern Indian history and international relations.Nitin DesaiFormer Under-Secretary General of the United NationsThis is a reference work on India at the UN General Assembly which not only records the Indian government's concerns on contemporary events, but provides a significant record, with explanatory footnotes, of world history from 1946 to 2018. This excellent collection will be valued by scholars of international relations and India's role as successive administrations finessed their policies to meet the needs of a changing world.Krishnan SrinivasanFormer Secretary, Ministry of External Affairs, GoIIndia's engagement with the United Nations, particularly the speeches and interventions in the General Assembly, has been a defining feature of India's foreign policy. India's stature as a key player in the international system has been reflected in the key concerns that it has championed through the UNGA. This comprehensive volume is an invaluable guide for academics and practitioners alike. It must be read by anyone looking for the moral compass that has guided the direction of India's foreign policy as well as to understand the real politic which has dominated New Delhi's thinking in recent years. A brilliant effort by the Editors to produce an incomparable resource!!Amitabh Mattoo, PadmashriProfessor, School of International Studies, Jawaharlal Nehru University, New Delhi andHonorary Professor of International Relations, University of Melbourne India has always stood for multilateralism as enshrined in the ethos of UN. The country also played a significant role in finalizing the UN Development Agenda 2030. Currently, when the world is striving to attain the Sustainable Development Goals (SDGs) for inclusive growth, the present volume is very timely and would serve as a useful reference for those who are trying to understand the evolution of multilateralism.Professor Sachin Chaturvedi, Director General, Research and Information System for Developing Countries (RIS), New DelhiIn 2015 India completed seventy years of her association with the United Nations. To commemorate India's association of over seventy years with this world body the Netaji Institute for Asian Studies, Kolkata, and the West Bengal Federation of United Nations Associations initiated a project to document this relationship between the United Nations and India, seeking to bring together speeches delivered by Indian representatives before the various forums of the world body.

The United Nations has always been held in high esteem in India, particularly during the Nehru years when an internationally minded Prime Minister ensured that India's voice would be heard in global debates on security, development, human rights and race relations. The evolving views of all Indian Governments on these matters were reflected in the opening statements made by heads of the Indian delegation, usually the Prime Minister or Foreign Minister, at the September General Assembly Session of the United Nations. This volume brings together these opening statements from 1945 onwards and presents in effect a history of India's international stance on issues of national and global concern. It is an invaluable resource for any student of modern Indian history and international relations.Nitin DesaiFormer Under-Secretary General of the United NationsThis is a reference work on India at the UN General Assembly which not only records the Indian government's concerns on contemporary events, but provides a significant record, with explanatory footnotes, of world history from 1946 to 2018. This excellent collection will be valued by scholars of international relations and India's role as successive administrations finessed their policies to meet the needs of a changing world.Krishnan SrinivasanFormer Secretary, Ministry of External Affairs, GoIIndia's engagement with the United Nations, particularly the speeches and interventions in the General Assembly, has been a defining feature of India's foreign policy. India's stature as a key player in the international system has been reflected in the key concerns that it has championed through the UNGA. This comprehensive volume is an invaluable guide for academics and practitioners alike. It must be read by anyone looking for the moral compass that has guided the direction of India's foreign policy as well as to understand the real politic which has dominated New Delhi's thinking in recent years. A brilliant effort by the Editors to produce an incomparable resource!!Amitabh Mattoo, PadmashriProfessor, School of International Studies, Jawaharlal Nehru University, New Delhi andHonorary Professor of International Relations, University of Melbourne India has always stood for multilateralism as enshrined in the ethos of UN. The country also played a significant role in finalizing the UN Development Agenda 2030. Currently, when the world is striving to attain the Sustainable Development Goals (SDGs) for inclusive growth, the present volume is very timely and would serve as a useful reference for those who are trying to understand the evolution of multilateralism.Professor Sachin Chaturvedi, Director General, Research and Information System for Developing Countries (RIS), New Delhi

Since AO and BY has been shown to be indiscriminately added in food and oil and both have genotoxic and carcinogenic/mutagenic potential. Hence, following studies are proposed as a part of this dissertation to fill up the above mentioned lacuna in argemone oil and butter yellow intoxication. Reproductive toxicity: Consumption of edible oil adulterated with argemone oil (AO) is also presumed to be one of the factors for reduction in sperm count and we have observed that alterations in germ cell apoptosis by a disruption in contact mediated communication between the Sertoli cells and germ cells, may subsequently lead to testicular impairment. Hepatic Toxicity: The study suggests that AO and BY treatment may cause oxidative stress and diminished phase I & II enzymes leading to accumulation of parent compound (s) or their metabolites which may results in the formation of liver cancer. Carcinogenic potential in gall bladder in vitro and in vivo study suggests that AO and BY are responsible for producing gall bladder carcinoma in mice along with stone formation in AO exposure.

The objective of this study was to understand the pitfalls of the poor oocyte cleavage and subsequent embryo production by assessing the developmental competence of the oocytes in buffalo using parthenogenesis as a model which was compared with IVF (natural activation). Buffalo ovaries were collected from slaughter house and matured oocytes were subjected to either IVF (control) or chemical activation (treatment)[7% ethanol (ET)for 7 min + 2.5 mM 6-Di methyl amino purine (6-DMAP) for 4 hr, or 7% ET for 7 min + 10 ug/ml Cycloheximide (CHX) for 6 hr or 7% ET for 7 min + 2.5 mM 6-DMAP + 10 ug/ml CHX for 6 hr]. Fertilized and chemically activated oocytes were cultured in mSOF medium for 8 days to study embryo development.In conclusion, the results of parthenogenesis, revealed that buffalo oocytes had better inherent developmental competence and the poor cleavage and embryo development following IVF, in our study, may partly be due to the poor quality of frozen-thawed sperm, improper sperm capacitation and/ or fertilization. Further, high ambient temperature adversely affected the cleavage and embryo development following IVF.

Beginning Apache Cassandra Development introduces you to one of the most robust and best-performing NoSQL database platforms on the planet. Apache Cassandra is a document database following the JSON document model. It is specifically designed to manage large amounts of data across many commodity servers without there being any single point of failure. This design approach makes Apache Cassandra a robust and easy-to-implement platform when high availability is needed.Apache Cassandra can be used by developers in Java, PHP, Python, and JavaScript—the primary and most commonly used languages. In Beginning Apache Cassandra Development, author and Cassandra expert Vivek Mishra takes you through using Apache Cassandra from each of these primary languages. Mishra also covers the Cassandra Query Language (CQL), the Apache Cassandra analog to SQL. You'll learn to develop applications sourcing data from Cassandra, query that data, and deliver it at speed to your application's users.Cassandra is one of the leading NoSQL databases, meaning you get unparalleled throughput and performance without the sort of processing overhead that comes with traditional proprietary databases. Beginning Apache Cassandra Development will therefore help you create applications that generate search results quickly, stand up to high levels of demand, scale as your user base grows, ensure operational simplicity, and—not least—provide delightful user experiences.