Bøger af Rosa Elena Bustos Cruz

Previous studies carried out by the Biosensor Research Group of the Institute of Clinicaland Experimental Transfusion Medicine at the Tübingen University had successfullydemonstrated determination of various blood types through the interaction oferythrocytes with immobilised antibodies on a QCM. These studies have opened thepossibility to test new applications of this technique for the study of infectious diseases.In our case, studies of the erythrocyte life cycle of P. falciparum, particularly during the lastsix hours preceding the merozoite release and studies related to reinfection of bymerozoites were the focus of our investigation.Release of malaria parasites of P. falciparum from infected erythrocyte at the end of theirasexual erythrocyte cycle occurs approximately every 48 hours, asynchronously in parasiteculture and synchronously in vivo. This process is poorly studied due to: (I) merozoiterelease is a very short event (