Bøger af Ravikumar Kurup

Climate change leads to endosymbiotic archaeal growth. Archaea has got methanogenic archaeal selenoproteins and uses the cellular selenium reserves and depletes selenium from the human system. This leads on to decreased cholesterol synthesis. Archaea also has got cholesterol oxidase activity and uses cholesterol for its energetics. The depletion of cholesterol leads to increased production of HMG CoA reductase enzyme, the rate limiting step in cholesterol synthesis. The increased production of HMG CoA reductase leads to defective processing of the HMG CoA reductase molecule making it antigenic. The inhibition of HMG CoA reductase by antiHMG CoA reductase antibody inhibits the isoprenoid pathway and synthesis of CoQ producing mitochondrial dysfunction. This leads to increased glycolytic activity and generation of the Warburg phenotype. Endosymbiotic archaea mediated autoimmune mitochondrial dysfunction and Warburg phenotype can lead on to climate change related tropical syndromes.

Neanderthal genes have been described in the homo sapien population. The Neanderthal brain structure results in female dominance and matriarchal social patterns. The Neanderthal phenotype is due to symbiosis by actinidic archaea using cholesterol as an energy substrate. The increasing cholesterol catabolism by actinidic archaea results in depletion of cholesterol from the body. This produces inhibition of estrogen and testosterone synthesis. This results in an asexual state and androgynous behaviour. The adult onset autistic phenotypes consequent to archaeal endosymbiosis lack social skills and graces required for social contact leading to inhibition of spontaneous normal heterosexual behaviour and family life as well as interactions. There would be an over reliance or instantaneous gratification given by the internet and artificial intelligence. This leads to break down of human relations producing the world of asexual infertile population of herbivores. The adult autistic asexual digisexual phenotypes will regenerate the population by cloned cyborgs and asexual reproduction.

The endosymbiotic archaea regulates human functions and species type and depends upon the colonic archaea whose density is determined by the fibre intake. The colonic archaeal population density depends upon dietary fibre intake. Populations with low fibre intake have lesser density of colonic archaeal microflora and endosymbiotic archaea. Endosymbiotic archaea contributes to neanderthalisation of the species. Populations consuming a high saturated fat and protein diet with low fibre intake tend to get increased endosymbiotic archaeal growth and are neanderthalised. Populations with high fibre intake up to 80 g/day tend to have reduced archaeal density in the colon and reduced archaeal endosymbiosis contributing to homo sapienisation of the population. Thus fibre intake regulates the endosymbiotic archaeal density and type of human species. Thus dietary fibre deficiency can lead to civilizational diseases and emerging infections. Dietary fibre is regulatory substance for the neuronal, immune, genomic and endocrine system.

Dietary fibre can alter the colonic microflora. High fibre intake suppresses colonic archaeal growth and archaeal endosymbiosis. High fibre diet suppresses endosymbiotic archaeal growth leading onto homo sapienisation of the species. High fibre diet leads to increased generation of butyrate and HDAC inhibition leading onto expression of the HERV genes & their reintegration into the genome. HERV jumping genes contributes to the dynamicity of the genome and is important in the evolution of synaptic connectivity and the homo sapien neocortex. Low fibre diet increases colonic archaeal growth and archaeal endosymbiosis contributing to neanderthalisation of the species and the brain. Low fibre diet and reduced levels of butyrate contributes to modulation of histone acetylation & reduced generation of HERV sequences, genomic rigidity & reduced synaptic connectivity. This leads to cerebral cortical suppression & cerebellar dominance contributing to neanderthalisation of the brain and species. Neanderthalisation of the brain leads to a cerebellar cognitive affective disorder contributing to a civilization which is dominated by nationalism, anarchy, violence, paganism and anarcho-capitalism