Bøger af Joseph Loscalzo

The Voice of Clinical ReasonHarrison's Principles of Internal Medicine is the world's most trusted clinical medicine text-and a superb resource for learning the art and science of clinical reasoning. Recognized by healthcare professionals worldwide as the leading authority on applied pathophysiology and clinical medicine, Harrison's Principles of Internal Medicine provides the informational foundation you need for the best patient care possible. This new edition is fully updated with timely new chapters and essential updates across the spectrum of internal medicine. Harrison's Principles of Internal Medicine stands as the benchmark for authoritative, practical information on patient care and the pathogenesis and clinical management of symptoms and signs and specific diseases. Written and edited by the world's top experts in their respective fields, this landmark guide provides the comprehensive, accurate, and essential coverage of the pathogenesis, diagnosis, and treatment of disease. Harrison's is world-renowned as the most authoritative source for: . Descriptions of disease mechanisms and how the clinician can apply that knowledge for the best patient care and optimal diagnosis and treatment of specific diseases . Clear, concise schemas that facilitate the generation of differential diagnoses to reason efficiently through complex real world clinical cases. The physiologic and epidemiologic basis of signs and symptoms, which are covered through a wealth of unsurpassed expert guidance and linked to the disease-specific chapters that follow. Updated clinical trial results and recommended guidelines . Excellent and extensive visual support, including radiographs, clinical photos, schematics, and high-quality drawings. Coverage of both therapeutic approaches and specific treatment regimens. Practical clinical decision trees and algorithms. Organ-specific sections, with clinically relevant pathophysiology and practical clinical advice on the approach to the patient, strategies towards building a differential diagnosis, outstanding clinical algorithms and diagnostic schema, a wealth of clinical images and diagrams, current clinical guidelines, general and specific approaches to therapyHarrison's remains the most trusted resource in a world influenced by endless sources of medical information. The most timely and comprehensive updates from the world's top experts are featured in the 21st edition: . Current coverage of the diagnosis and treatment of diseases, from COVID to dementia to sepsis to multiple sclerosis to lung cancer. Updated content that reflects new approved therapeutics and new practice-changing guidelines and evidence summaries. More than 1000 clinical, pathological, and radiographic photographs, diagnostic and therapeutic decision trees, and clear schematics and diagrams describing pathophysiologic processes. More than a dozen atlases featuring curated collections of visual aspects of diagnosis and management. Complete, updated curation and synthesis of primary medical literature which incorporates current data from major studies and clinical trials . Clinical reasoning resources and helpful disease/presentation schemas. Clinically relevant coverage of disease mechanics and pathophysiology, and related therapeutic mechanisms

Tommy Shotwell. Ex-Cop. Former FBI and CIA agent. Private Investigator. Compulsive Gambler. Business was not looking good for Tommy Shotwell. Since opening his own private investigator company he had only worked on five cases. Enter Christine Mist. Daughter of multi-millionaire Anthony Mist, with an offer to buy half the agency if Tommy Shotwell would act as a mentor. It had long been her dream to be a private investigator, but Christine had an ulterior motive. Christine's mother had been killed in a lab accident a year earlier, but Christine believes she was murdered. A mysterious letter sent from her mother before she died must mean something other than the gibberish it seemed to be. And Christine wanted answers . . . and revenge. When she shows the letter to Tommy his mood immediately changes from one of humor to a cold-seriousness he rarely shows. For Tommy, the letter has brought up a past he could not forget, a past that has brought him to this present, a past with a nemesis he thought he had left far behind.The Jackal. With the new influx of cash the sale of half his agency would bring, perhaps he could get one step closer to bringing down the person responsible for destroying his life once and for all.

When Maria Velasquez began to hear the thoughts of others, she knew life would never be the same; but the possibility she could be the savior of not only the world, but an entire galaxy had never crossed her mind. Now Maria finds herself on a journey of self-discovery that takes her from the suburbs of Manhattan to a planet buried deep in the subgalaxy.Maria's guide on her journey is Wynn, the descendant of Paladins sent here to protect Earth from the impending danger posed by the evil Czar Caiphas, leader of the Galactic Socialist Regime. Their mission is to watch and wait for an earthling to emerge whom they believe could be the Heir to Master Suuth, an ancient Master of the Paladins secreted to our world to protect him from the Czar.Accessible through a rift in space, a phenomenon of light and gravity known as the Cold Star, the subgalaxy is a realm ruled by the opposing forces of magic and faith. Ripe with political intrigue and a never-ending state of galactic war, the clashing of our two galaxies promises an explosive result.Can Wynn and Maria unlock the secrets of the Master's Heir and defeat Czar Caiphas and his Knights? Cold Star is a fast-paced futuristic Galactic Fantasy certain to transport you through time and space and leave you wanting more.

Two Doctors, two tales.In Paradox, Doctor Otis Milo has goneto Mars to investigate the ArgyrePlanitia Impact Basin, and a strange yetfamiliar structure buried in the Martiansoil. What he finds is the key to his past and his future.In Organ Farm, Doctor Harbaugh hasmastered human cloning, and has set upa farm of perfect organ donors for theelite few who could afford to clone theirchildren before they are born. But whenthe debate over what does and does notconstitute human life comes intoquestion, the story takes a horrific turn.

Nitrite and Nitrate in Human Health and Disease delivers a comprehensive review of nitrite and nitrate biology, from basic biochemistry to the complex physiology and metabolism of these two naturally occurring molecules in the human body. Well-organized and well referenced chapters cover the rich history of nitrite and nitrate, sources of exposure, and the physiological effects when consumed through foods containing nitrite and nitrate. The chapters are written by leading experts, all of whom share their research and perspectives in order to help define the context for benefits vs. any potential risks associated with nitrite and nitrate use, either through dietary ingestion or therapeutic dosing. This diverse collection of authors includes vascular biologists, physiologists, physicians, epidemiologists, cancer biologists, registered dieticians, chemists, and public health experts from five countries in both academia and government. Nitrite and Nitrate in Human Health and Disease provides a balanced view of nitric oxide biochemistry, and nitrite and nitrate biochemistry in physiology and in the food sciences.