Bøger af Anna Robinson

Non coding RNAs (ncRNAs) consist of a large portion of poly-A tailed mature RNAs. They are single stranded molecules, which are involved in the regulation of gene expression at the post-transcriptional level in a cell. There are two types of ncRNAs, which are regulatory ncRNAs and infrastructural ncRNAs. Small interfering RNAs (siRNAs), microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and piwi-interacting RNAs (piRNAs) are the four types of regulatory ncRNAs. The expression of thousands of genes is regulated through ncRNAs and this regulation can take place in either cis or trans. NcRNAs must be integrated into regulatory networks for the identification of molecular driver events. The two largest members of the ncRNA family, which includes long non coding RNA (lncRNA) and micro RNA (miRNA), play significant regulatory roles in gene expression. They are also involved in a variety of physiological processes including programmed cell death. This book unravels the recent studies on non coding RNA biology. It attempts to understand the regulation of non coding RNAs. For all those who are interested in ncRNAs, it can prove to be an essential guide.

Ribonucleic acid (RNA) is a nucleic acid which plays an integral role in coding, decoding, regulation and expression of genes. Some of the different types of RNA are messenger RNA, non-coding RNA, small chain RNA and long chain RNA. Messenger RNA transmits the information from the DNA to the ribosome. Non-coding RNAs (ncRNAs) regulate the expression of genes at the transcriptional and post-transcriptional level. There are two major subtypes of regulatory non-coding RNAs, namely, long non-coding RNA (lncRNA) and micro RNA (miRNA). They both interact not only with each other but also with other intracellular components to modulate the inter-related steps and mediators of regulated forms of cell death, such as necrosis and apoptosis. As a result, they could be in a key position for regulating cell death. This book provides significant information to help develop a good understanding of the molecular biology of RNA. Those with an interest in this field would find it helpful.

A collection of poems, set in and around the centre of London that depict a capital both familiar and alien, peopled with figures contemporary and historical: from the residents of present-day Lambeth, to the victims of Jack the Ripper, and to those whose spirits are still embedded in the reflections of a plate-glass office window.