Bøger i Woodhead Publishing Series in Biomaterials serien

Metallic Biomaterials Processing and Medical Device Manufacturing details the principles and practices of the technologies used in biomaterials processing and medical device manufacturing. The book reviews the main categories of metallic biomaterials and the essential considerations in design and manufacturing of medical devices. It bridges the gap between the designing of biomaterials and manufacturing of medical devices including requirements and standards. Main themes of the book include, manufacturing, coatings and surface modifications of medical devices, metallic biomaterials and their mechanical behaviour, degradation, testing and characterization, and quality controls, standards and FDA regulations of medical devices. The leading experts in the filed discuss the requirements, challenges, recent progresses and future research directions in the processing of materials and manufacturing of medical devices. Metallic Biomaterials Processing and Medical Device Manufacturing is ideal for those working in the disciplines of materials science, manufacturing, biomedical engineering, and mechanical engineering.Reviews key topics of biomaterials processing for medical device applications including metallic biomaterials and their mechanical behavior, degradation, testing and characterizationBridges the gap between biomaterials design and medical device manufacturingDiscusses the quality controls, standards, and FDA requirements for biomaterials and medical devices

Handbook of Biomaterials Biocompatibility is a systematic reference on host response to different biomaterials, taking into account their physical, mechanical and chemical properties. The book reviews recent progress in the design and study of biomaterials biocompatibility, along with current understanding on how to control immune system response. Sections provide the fundamental theories and challenges of biomaterials biocompatibility, the role of different biomaterials physicochemical surface properties on cell responses, cell responses to different physicochemical properties of polymers, ceramics, metals, carbons and nanomaterials, and biomaterials in different tissues, such as the cardiac, nervous system, cartilage and bone. This resource will be suitable for those working in the fields of materials science, regenerative engineering, medicine, medical devices and nanotechnology.Reviews the fundamental theories and challenges of biomaterials biocompatibility, including an overview of the standards and regulationsProvides an overview on the cellular and molecular mechanisms involved in host responses to biomaterialsSystematically looks at cellular response and tissue response to a wide range of biomaterials, including polymers, metals, ceramics, alloys and nanomaterials

Advanced 3D-Printed Systems and Nanosystems for Drug Delivery and Tissue Engineering explores the intricacies of nanostructures and 3D printed systems in terms of their design as drug delivery or tissue engineering devices, their further evaluations and diverse applications. The book highlights the most recent advances in both nanosystems and 3D-printed systems for both drug delivery and tissue engineering applications. It discusses the convergence of biofabrication with nanotechnology, constructing a directional customizable biomaterial arrangement for promoting tissue regeneration, combined with the potential for controlled bioactive delivery. These discussions provide a new viewpoint for both biomaterials scientists and pharmaceutical scientists. Shows how nanotechnology and 3D printing are being used to create systems which are intelligent, biomimetic and customizable to the patientExplores the current generation of nanostructured 3D printed medical devicesAssesses the major challenges of using 3D printed nanosystems for the manufacture of new pharmaceuticals

Libraries have historically played a role as a community builder, providing resources and spaces where knowledge can be archived, shared and created. They can also play a pivotal role in fostering the public''s understanding of science and scientific processes. From makerspaces to data visualization labs to exhibits, many libraries already delve into scientific explorations and many more could join them. Scientists often need to include "broader impacts" goals in grant proposals, but they might not know where to begin or feel that they do not have the time to devote to public engagement. This is where libraries and librarians can help. Research in science communication also supports tapping into libraries for public engagement with science. Studies show that it is important for scientists to present findings in an apolitical way-not aligning with one solution or one way of thinking and not being seen as an activist (Druckman, 2015; Jamieson & Hardy, 2014). One of the core tenets of librarians and libraries is to present information in a neutral way. Research also shows that Informal conversations about science can have a greater effect on people than reading about it online or hearing about it on the news (Eveland & Cooper, 2013). Again, libraries can play a role in fostering these types of conversations. Given this landscape, this book will demonstrate concrete ways that libraries and librarians can play a role in fostering public engagement with science. In addition to background information on the current landscape of public knowledge and understanding of science, it will also include best practices and case studies of different types of programming and services that libraries can offer. Often libraries do not jump to mind when people think about science education or science literacy, and many librarians do not come from a science background. Literature on science programming and sharing science is largely absent from the library field. This book will help give confidence to librarians that they can participate in engaging the public with science. At the same time, it will provide a conduit to bring informal science educators, communication officers from universities or research organizations who share scientific discoveries with the public, and librarians together to explore ways to align their work to promote scientific literacy for all.Demonstrates concrete ways that libraries and librarians can play a role in fostering public engagement with scienceFeatures best practices and case studies of different types of programming and services that libraries can offerProvides a conduit to bring informal science educators, communication officers, and librarians together to explore ways to align their work to promote scientific literacy

Biosynthetic Polymers for Medical Applications provides the latest information on biopolymers, the polymers that have been produced from living organisms and are biodegradable in nature. These advanced materials are becoming increasingly important for medical applications due to their favorable properties, such as degradability and biocompatibility. This important book provides readers with a thorough review of the fundamentals of biosynthetic polymers and their applications. Part One covers the fundamentals of biosynthetic polymers for medical applications, while Part Two explores biosynthetic polymer coatings and surface modification. Subsequent sections discuss biosynthetic polymers for tissue engineering applications and how to conduct polymers for medical applications. Comprehensively covers all major medical applications of biosynthetic polymersProvides an overview of non-degradable and biodegradable biosynthetic polymers and their medical usesPresents a specific focus on coatings and surface modifications, biosynthetic hydrogels, particulate systems for gene and drug delivery, and conjugated conducting polymers

Bone Repair Biomaterials: Regeneration and Clinical Applications, Second Edition, provides comprehensive reviews on materials science, engineering principles and recent advances. Sections review the fundamentals of bone repair and regeneration, discuss the science and properties of biomaterials used for bone repair, including metals, ceramics, polymers and composites, and discuss clinical applications and considerations, with chapters on such topics as orthopedic surgery, tissue engineering, implant retrieval, and ethics of bone repair biomaterials. This second edition includes more chapters on relevant biomaterials and a greatly expanded section on clinical applications, including bone repair applications in dental surgery, spinal surgery, and maxilo-facial and skull surgery. In addition, the book features coverage of long-term performance and failure of orthopedic devices. It will be an invaluable resource for researchers, scientists and clinicians concerned with the repair and restoration of bone.Provides a comprehensive review of the materials science, engineering principles and recent advances in this important areaPresents new chapters on Surface coating of titanium, using bone repair materials in dental, spinal and maxilo-facial and skull surgery, and advanced manufacturing/3D printingReviews the fundamentals of bone repair and regeneration, addressing social, economic and clinical challengesExamines the properties of biomaterials used for bone repair, with specific chapters assessing metals, ceramics, polymers and composites

Surface modification of biomaterials can ultimately determine whether a material is accepted or rejected from the human body, and a responsive surface can further make the material "smart" and "intelligent". Switchable and Responsive Surfaces and Materials for Biomedical Applications outlines synthetic and biological materials that are responsive under different stimuli, their surface design and modification techniques, and applicability in regenerative medicine/tissue engineering,  drug delivery, medical devices, and biomedical diagnostics. Part one provides a detailed overview of switchable and responsive materials and surfaces, exploring thermo-responsive polymers, environmentally responsive polyelectrolytes and zwitterionic polymers, as well as peptide-based and photonic sensitive switchable materials. Further chapters include a detailed overview of the preparation and analysis of switchable polymer brushes and copolymers for biomedical application. Part two explores the biological interactions and biomedical applications of switchable surfaces, where expert analysis is provided on the interaction of switchable surfaces with proteins and cells. The interaction of stimuli-sensitive polymers for tissue engineering and drug delivery with biosurfaces is critiqued, whilst the editor provides a skillful study into the application of responsive polymers in implantable medical devices and biosensors. A comprehensive overview of switchable and responsive materials and surfacesIncludes in depth analysis of thermo-responsive polymers, photonic sensitive materials and peptide-based surfacesDetailed exploration of biological interactions of responsive and switchable surfaces, covering stimuli-sensitive polymers for drug delivery, surfaces with proteins/cells and application of polymers in medical devices

Handbook of Ionic Substituted Hydroxyapatites provides scientists and researchers with comprehensive information on the synthesis processes of hydroxyapatite, also explaining the application of substituted hydroxyapatite. The book''s content is very structured and explanatory, starting with a detailed overview of biological apatite in bones and teeth, as well as a presentation of the analytical tools for hydroxyapatite. Bioceramics and the relative modern and emerging processing techniques are covered, as is 3-D printing, which has gained increasing importance within biomedical materials and in the use of hydroxyapatite in tissue engineering. Finally, the advantages and disadvantages of using ionic substitutions in clinical application are presented. Students and researchers in disciplines, such as Material Science, Ceramics, and Bioengineering will find this book to be very helpful in their work. It will also be a valuable resource for practitioners and surgeons in orthopedics, perio/implantology and maxillo-facial disciplines, and professionals working in R&D in ceramics and pharmaceuticals.Provides responses to the lack of scientific information about hydroxyapatites for biomedical applicationsSolves researchers'' issues regarding phase changes with respect to substituted ions and how these substitutions can alter/improve the properties of stoichiometric hydroxyapatiteExplains modern clinical applications and the effects of apatites within biomedical applications Includes both the advantages and disadvantages of using ionic substitutions in clinical application

Mineralized Collagen Bone Graft Substitutes presents a comprehensive study of biomimetic mineralized collagen, synthesized in vitro, a next generation biomaterial for bone regeneration. By focusing both on fundamental research and the clinical use of this novel material, the book provides a complete examination, from bench to bedside. Chapters discuss natural bone and familiar biomaterials for bone repair, the preparation and safety of mineralized collagen, products made of mineralized collagen, and present clinical case studies. This book is an invaluable and unique resource for researchers, clinicians, students and industrialists in the area of orthopedics and dentistry.Provides a deep analysis of synthetic collagen, from bench to bedsideSystematically examines the structure, principles, properties, biomimetic synthesis and characterization of mineralized collagen for bone repairIncludes case studies that look at a range of clinical bone repair applications of Mineralized collagen and their clinical results

Bioceramics: For Materials Science and Engineering provides a great working knowledge on the field of biomaterials, including the interaction of biomaterials with their biological surroundings. The book discussees the biomedical applications of materials, the standpoint of biomedical professionals, and a real-world assessment of the academic research in the field. It addresses the types of bioceramics currently available, their structure and fundamental properties, and their most important applications. Users will find this to be the only book to cover all these aspects. Acts as the only introductory reference on bioceramics that covers both the theoretical basics and advanced applications Includes an overview of the key applications of bioceramics in orthopedics, dentistry and tissue engineeringUses case studies to build understanding and enable innovation

Biomedical, Therapeutic and Clinical Applications of Bioactive Glasses is an essential guide to bioactive glasses, offering an overview of all aspects of the development and utilization of this cutting-edge material. The book covers vital issues, including mesoporosity, encapsulation technologies, scaffold formation and coatings for a number of applications, including drug delivery, encapsulation, scaffolds and coatings. Readers will gain a strong understanding and practical knowledge of the therapeutic aspects of bioceramics, with a focus on glasses from a clinical point-of- view. Researchers, students and scientists involved in bioceramics, bone tissue engineering, regeneration and biomedical engineering will find this to be a comprehensive resource. Presents detailed coverage of bioactive glasses, including technologies and applicationsIncludes all the major development areas related to bioactive glasses, enabling readers to understand the latest researchConsiders the potential future developments of bioactive glasses as a drug carrier

Traditional dental materials such as metals and ceramics have a number of disadvantages such as cost and the significant damage caused in grinding to make space for such reconstructions. Fiber-reinforced composites (FRCs) are a novel group of dental materials characterized by fibrous fillers that are being increasingly used in place of traditional prosthodontic materials. They allow fabrication of minimally invasive, lightweight, durable and biocompatible restorations. This book will provide clinicians and students with theoretical and clinical guidelines to use the FRCs for dental applications. The book begins with an introduction to the fundamentals of FRCs in dentistry. Further chapters cover the treatment possibilities, fabrication and application procedures of FRCs, followed by information on care and maintenance.