Bøger i Synthesis (CHUP) serien

In the fall of 1980, Genentech, Inc, a little-known California genetic engineering company, became the overnight darling of Wall Street, raising over $38 million in its initial public stock offering. This title offers portraits of the people significant to Genentech's science and business, including co-founders Herbert Boyer and Robert Swanson.

Focuses on Herman Boerhaave (1668-1738), a Dutch medical and chemical professor whose work reached a wide, educated audience and became the template for chemical knowledge in the eighteenth century. This title reveals how Boerhaave restructured and reinterpreted various practices from diverse chemical traditions - including craft chemistry.

Brings alchemy out of the shadows and restores it to its important place in human history and culture. By surveying what alchemy was and how it began, developed, and overlapped with a range of ideas and pursuits, this title illuminates the practice.

After World War II, the US Atomic Energy Commission (AEC) began mass-producing radioisotopes, sending out nearly 64,000 shipments of radioactive materials to scientists and physicians by 1955. This title tells the story of how these radioisotopes, which were simultaneously scientific tools and political icons, transformed biomedicine and ecology.

Today's science tells us that our bodies are filled with molecular machinery that orchestrates all sorts of life processes. When we think, microscopic "channels" in our brain cells' membranes open and close; when we run, tiny "motors" in our muscle cells' membranes spin; and when we see, light operates "molecular switches" in our eyes and nerves. A molecular-mechanical vision of life has become commonplace in both the halls of philosophy of science departments and the offices of drug companies developing "proton pump inhibitors" or medicines such as Prozac.  Membranes to Molecular Machines explores just how late twentieth-century science came to think of our cells and bodies this way. This story is told through the lens of membrane research, an unwritten history at the crossroads of molecular biology, biochemistry, physiology and the neurosciences, that directly feeds into today's synthetic biology as well as nano- and biotechnology. Mathias Grote shows how these sciences have not only made us think differently about life, they have, by reworking what membranes and proteins represent in laboratories, allowed us to manipulate life as "active matter" in new ways. Covering the science of biological membranes since the mid-1960s, this book connects that history to contemporary work with optogenetics, a method for stimulating individual neurons using light, and should appeal to scholars interested in the intersection of chemical research and the life sciences.

"For centuries, historians have speculated about the life of Katherine Jones, Lady Ranelagh. The details of her relationship with Robert Boyle, her younger brother, have mostly remained a mystery, even though Boyle, "the father of chemistry," spent the last twenty-three years of his life residing in her home, with the two dying only one week apart in 1691. The dominant depiction of Lady Ranelagh shows her as a maternal figure to Boyle or as a patroness of European intellectuals of the Hartlib circle. Yet neither of these portraits captures the depth of her intellect or range of her knowledge and influence. Philosophers, mathematicians, and religious authorities sought her opinion on everything from decimalizing the currency to producing Hebrew grammars. Lady Ranelagh practiced medicine alongside distinguished male physicians, treating some of the most elite patients in London, and her medical recipes and testimony concerning the philosophers' stone both gained international circulation. She was an important influence on Boyle and a self-standing historical figure in her own right. Chemistry's Sister fills out Lady Ranelagh's legacy in the context of a historically sensitive and nuanced interpretation of gender, science, and religion. It reveals how one elite seventeenth-century woman, without suffering attacks on her "modesty," managed to gain the respect of diverse contemporaries, effect social change, and shape science for centuries to come"--

Drawing on a wealth of archival material, this book combines legal, medical, and business history to offer a sweeping new interpretation of the origins of the complex and often troubling relationship between the pharmaceutical industry and medical practice today.