Bøger i Drug Discovery serien

This book will provide an invaluable guide to epigenetics, one of the fastest moving fields in drug discovery, for medicinal chemists working in academia and in the pharmaceutical industry.

Peptide Therapeutics is an essential reference work for students and researchers, in both academia and industry, with an interest in learning about Chemistry Manufacture and Control (CMC), and facilitating the development and manufacture of peptide-based drugs.

Pharmaceutical Formulation provides an up to date source of information for all who wish to understand the principles and practice of formulation in the drug industry.

This book is a forward-looking analysis of a number of key areas for kinase inhibition in the coming years.

This book addresses approaches to the treatment of retinal diseases, targeting common processes and components.

This book gives an overview of a field where several disciplines have come together towards individualised, safer therapies, and better monitoring of disease and drug action and distribution.

MicroRNAs in Diseases and Disorders highlights the role of miRNAs in the development and progression of a variety of diseases and the utilization of miRNA targets in treatment. This book also includes the use of miRNAs as diagnostic and prognostic biomarkers for disease.

This book provides a comprehensive overview from the leading academic and industrial experts on recent developments, scope and limitations in this dynamically growing research area; an ideal reference work for researchers in drug discovery and chemical biology as well as advanced students.

A book useful to postgraduate students and researchers in medicinal chemistry and pharmacology, as well as specialists in the acute brain injury field.

Drug Discovery for Leishmaniasis aims to provide a perspective of the current treatments and their challenges, blended with the emerging strategies and methodologies that will drive new target appraisals and drug developments, as well as addressing the molecular basis of resistance in Leishmania.

This book highlights the new frontiers in chemical biology and describes their impact and future potential in drug discovery.

An invaluable guide to successful practice in neglected tropical diseases (NTDs) and highlights best practice to guide the ongoing drug discovery effort.

This is the first comprehensive description of the discovery and therapeutic potential of polyamine drugs.

This book considers the relationship between structure and function in G protein-coupled receptors (GPCRs) and the implications for drug design.

This is the first book to examine the future opportunities and challenges in the development of drugs which target kinases

Shows how different parts of the drug discovery process have developed, with particular emphasis on quantitative aspects and possible future progress.

Intracellular cell signaling is a well understood process. However, extracellular signals such as hormones, adipokines, cytokines and neurotransmitters are vital to the signaling process and have been largely ignored in other works on signaling.

This thorough and up-to-date insight into predictive technologies considers what is on the horizon for safety prediction in human health.

This exemplary book gives an up-to-date perspective on the role of metal ions in neurodegeneration.

Describes proteolytic enzymes and their biological function to aid drug discovery by detailing methods of production and assay of the enzymes.

The focus of this new book is for medicinal chemists on the chemical agents that have been used, or might be required in the future, and the methods of synthesis for inserting the reporter groups. A key reference for academics, postgraduates, researchers, industrialists and professionals working in or joining this field.

This book provides up-to-date information on the use of transgenic mouse models in the study of neurodegenerative disorders. The editors have extensive knowledge and experience in this field and the book is aimed at undergraduates, postgraduates and academics.

Accounts in Drug Discovery describes recent case studies in medicinal chemistry with a particular emphasis on how the inevitable problems that arise during any project can be surmounted or overcome.

A volume that will provide a mechanism-based approach to understanding Chinese medicine for both Western and Eastern scientists.

New Tools to Interrogate Endocannabinoid Signalling comprehensively covers the innovative research into both natural and synthetic compounds. This timely volume will be a valuable resource to pharmaceutical researchers and medicinal chemists working in natural products and endocannabinoid drug discovery in academia and industry.

Antibody-drug conjugates are a promising areas of anticancer drug discovery, conveying several advantages, including the ability to select likely responders, efficient delivery of cytotoxic agents and reduced toxicity. This book describes payloads used to date and novel payloads that may be used clinically in the future.

Advances in Nucleic Acid Therapeutics provides a broad overview of techniques of contemporary interest in drug discovery.

Emerging Drugs and Targets for Alzheimer's Disease collects some of the most outstanding examples of new drugs currently in pharmaceutical development or new targets under the validation process that will reach the Alzheimer's drug market over the next few years as disease modifying drugs.

Written by medicinal chemists and ADMET scientists with a combined experience of over 300 years this aid to discovering drugs provides detailed coverage on absorption, distribution, metabolism, excretion and toxicology issues associated with new drugs.

With perspectives from academia and industry across a spectrum of techniques, this is a go-to volume for biophysicists, analytical chemists and medicinal chemists looking for a broad overview of techniques of contemporary interest in drug discovery.