Bøger i Advances in Biochemical Engineering/Biotechnology serien

This new volume introduces the applications of microfluidic systems to facilitate biotechnological and biomedical processes. It provides an overview on cutting-edge technologies, summarizes traditional and modern fabrication methods and highlights recent advances regarding the application of lab-on-a-chip (LoC) systems for bioanalytical purposes. This book is ideal for research scientists and students interested at the cross-section between biotechnology, chemistry and chemical engineering.

This book provides a comprehensive overview of current biosurfactant research and applications. Public awareness of environmental issues has increased significantly over the last decade, a trend that has been accompanied by industry demands for climate-friendly and environmentally friendly renewable raw materials. In the context of household products, biosurfactants could potentially meet this demand in the future due to their low ecotoxicity, excellent biodegradability, and use of renewable raw materials. The diversity of this class of molecules, which has only been marginally tapped to date, offers only an inkling of their future application potential. However, there are two main obstacles to their widespread commercial use on the growing surfactant market: the lack of attractive and competitive production technologies, and the limited structural diversity of commercially available biosurfactants. Addressing both of these core issues, this book will provide readers with a deeper understanding of the role of biosurfactants, including future opportunities and challenges.Chapter "e;Environmental Impacts of Biosurfactants from a Life Cycle Perspective: A Systematic Literature Review"e; is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

This book reviews the advances in data gathering and processing in the biotech laboratory environment, and it sheds new lights on the various aspects that are necessary for the implementation of intelligent laboratory architecture and infrastructure. Smart technologies are increasingly dominating our everyday lives and have become an indispensable part of the industrial environment. The laboratory environment, which has long been rather conservative, has also set out to adapt smart technologies with regards to Industry 4.0 and the Internet of Things (IoT) for the laboratory. Due to the heterogeneity of the existing infrastructure and the often complex work processes, standardization is slow, e.g. to implement device interfaces or standardized driver protocols, which are urgently needed to generate standardized data streams that would be immanent for post-processing of data.Divided into 9 chapters, this book offers an authoritative overview of the diverse aspects in the generation and recording of uniform data sets in the laboratory, and in the processing of the data and enabling seamless processing towards machine learning and artificial intelligence. In the first part of the book, readers will find more about high throughout systems, automation, robotics, and the evolution of technology in the laboratory. The second part of the book is devoted to standardization in lab automation, in which readers will learn more about some regulatory aspects, the SiLA2 standards, the OPC LADS (Laboratory and Analytical Device Standard), and FAIR Data infrastructure

This book provides a comprehensive and authoritative review of cyanobacteria and their applications as solar cell factories. Cyanobacteria are able to perform oxygenic photosynthesis and they are utilized in many different bioprocesses. The book covers two major aspects of a cyano-based bioprocess: the biological whole-cell catalyst and the technical environment in which the catalyst is applied. In the biocatalyst itself electron and carbon flow play an essential role for the performance of the cell and need to be tackled likewise for successful biocatalyst development. In the first chapters of this volume, cyanobacterial biotechnology and the fundamentals of cyanobacterial bioenergetics are introduced followed by an overview on tools and strategies for cyanobacteria engineering. Further on, examples of applications, engineering and production of different industrially relevant compounds in these organisms are provided, and finally process technology specific for cyanobacteria is covered. In this book, particular attention is given to topics such as cyanobacterial bioenergetics, metabolic engineering design strategies, utilizing cyanobacteria in biophotovoltaics, and production of pigments as well as photobiohydrogen in cyanobacteria, among others.This book will provide interested students and researchers in the area of photo-biotechnology with a deeper understanding of the cyanobacterial cell-factory, including the latest innovations and persistent challenges in the field.

This book reviews the development of cell-free production platforms and offers an authoritative perspective of the latest advances and methodologies in cell-free production systems. Readers will discover the biomanufacturing potential of in vitro biotransformation (ivBT) employing purified cascade multi-enzymes, the development of hydrogel-based multi-enzymatic systems for biosynthesis, and novel insights into the optimization of biocatalytic processes. Additionally, the book explores the cell-free production and regeneration of cofactors, shedding light on strategies to enhance the efficiency and sustainability of cellular processes.In this book, particular attention is given to the progress of cell-free in vitro evolution techniques for optimizing enzyme performance, and the book also presents the integration of rapid and finely-tuned expression systems for deployable sensing applications, revolutionizing the field of biosensing. The synthesis and electrophysiological analysis of multipass voltage-gated ion channels tethered in microsomal membranes are explored, providing a deep understanding of cellular function at the molecular level. Lastly, the book covers compartmentalized cell-free expression systems for building synthetic cells, showcasing the potential for constructing artificial cellular systems with unique functionalities.Given its breadth, this book appeals to academics, researchers, and professionals interested in the forefront of biotechnology, and together with the companion volume ¿Cell-free Macromolecular Synthesis¿, both books highlight the research progresses on the basic and applied research of cell-free production systems in the last few years, being invaluable resources in the field.Chapter ¿Cell-free synthesis and electrophysiological analysis of multipass voltage-gated ion channels tethered in microsomal membranes¿ is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.