Bøger af A. J. Larner

This book describes, extends, and illustrates the metrics of binary classification through worked examples.Worked examples based on pragmatic test accuracy study data are used in chapters to illustrate relevance to day-to-day clinical practice. Readers will gain an understanding of sensitivity and specificity and predictive values along with many other parameters.The contents are highly structured, and the use of worked examples facilitates understanding and interpretation.This book is a resource for clinicians in any discipline who are involved in the performance or assessment of test accuracy studies and professionals in the disciplines of machine learning or informatics wishing to gain insight into clinical applications of 2x2 tables.

This extensively revised second edition provides a comprehensive overview of transient global amnesia (TGA). First, it deals with the history of TGA before moving on to clinical and diagnostic features and differential diagnosis. Subsequent chapters then discuss the investigation and predisposing and precipitating factors for TGA before attempting to synthesise these many strands in order to formulate ideas about the pathogenesis of TGA. Each of the chapters is devoted to a practical and structured overview of the particular topic, with use of case studies to illustrate the material. Based in part on the author¿s experience of TGA cases over 20 years and in part on a review of the published literature, this book will hopefully enlighten clinicians from a broad range of medical backgrounds on the clinical features, investigation, and pathogenesis of TGA.Transient Global Amnesia is aimed at any clinician with an interest in, or who encounters patients with, acuteamnesia: neurologists, general physicians, old age psychiatrists, geriatricians, clinical neuropsychologists, and primary care physicians, as well as other professions allied to medicine with similar interests, such as members of memory assessment teams.

This expanded, updated third edition summarizes the pragmatic diagnostic accuracy studies of neurological signs and cognitive and non-cognitive screening instruments undertaken in the author's clinic in the context of day-to-day practice involving patients with cognitive disorders including dementia.

Understanding the cognitive aspects of neurological disorders is essential to manage effectively patients suffering from these conditions. This book begins by outlining the various cognitive domains and how these can be tested, before covering in depth the cognitive deficits seen in prototypical neurodegenerative cognitive disorders (Alzheimer's disease, frontotemporal dementias, Huntington's disease, prionoses) and other common neurological disorders that may be complicated by cognitive impairment (stroke, multiple sclerosis, Parkinson's disease, brain tumours). This second edition has been completely revised and updated, with new material added throughout, including two new chapters: 'Sleep-Related Disorders' and 'Psychiatric Disorders in the Cognitive Function Clinic'. This an essential reference for all neurologists, not just for those with an interest in cognitive disorders. General physicians and specialists who deal with endocrine, metabolic, vascular or infective disorders that may compromise cognitive function, and allied health professionals who work with cognitively impaired patients, will also find this text useful.